四川大学华西医院危重病2016年考博真题
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2016 年名词解释:生物转化蛋白模体信号肽细胞编程G蛋白简答:1,生物信息分子有哪些?细胞信号转导2,蛋白折叠过程3,酶的抑制剂有哪些4,细胞凋亡因子的作用5,蛋白分选机制论述:1, DNA复制RNA合成蛋白合成的保真2,DNA复性的影响因素3,你对合成生物学、系统生物学的认识2011年K乙他辅侑A任:人代谢屮的作川2、代谢调杠细胞水半的调i'i3、变构调肯和化学修饰的井同4、作川J DNA衣达的药物的机理•制述3类药物5、翻译施的蛋门质修饰2012年・、名詞解释(20分)1、RNA splicing2、岱号肚3、构住与构象4、蛋门硕模休令结构域5、SiRNA二、分析简答龛(32分)1、试述卜列冈素如何影响DNA的夂性过程<1)RIW ((2)低J * Tm 度(3〉高浓度的DNA 链2、«A»U冰的原理及其应川3>匝嘤细胞Mi'rW fYf哪叫?兀作川机制如何?4、仆•种混介液MA、B、C -种蛋m 这二种蛋门分了;1匕等电点如卜:A1M000,8.5; B 64000 , 5.9 : C 6000・6.0按分/讹和竽电点将J〔分肉纯化这三种蛋仏并列:||签定方汰.二论述題(48分)K DNA M制、RNA介成、蛋门质介成如何保证冀保戊性?2、细胞内们号传导及冀作川机制3、运川化物化学用I关掠理说明药物介理设讣2013年・、名诃解释(20分)K信号从2.诵导肚3.模休4.Gutn5 •转化二简签越1.DNA M制、转录和胡译如何保允2.什么朋抑制剂?简述右哪儿种抑制剂.分别冇什么待点?3・细胞倍号转导7、论述鬆K细胞核编码的蛋门的分选途径?2、Flftl 7个冈素足怎么影响DNA变性的,高浓度阳离仇低Tmffi, ft浓度的DNA ?3、列;I;朗个实鲨分肉纯化乐门.并说岀原理.蛋门分fWflPI分别为64000、8.0;18000、5.91 6000 . 6.0.2014 年・、名词解释1、RNA splicing2、Apoptosis3、Instructs enzyme4、Stemp cell engering5、Systemic biology二、简答悪K 例举关「2013年保学或生理学方Ifil91尔并说期冀上嘤内容及门<2 的见解2、DNA V兴的彩响W^:(l)Blwr浓度(2)隘度Tm (3)DNA 浓度3、un^t的比沾性测足\论述理1、H«;素与碳胺类药物的作用机制?2、允核生物与原核生物转杀麻的加I:Y J H井同?3、对r儿种人匸合成底物1刑一酶《i结介时•侑9底物納介的亲和力人小不同・怎样说明?2015 年仁名诃解释(40)K端粒(酶)2、两性a •螺旋3、G PCR4、G WAS5、磷酸无糖途径6、氏链II编码RNA7、朋体8、化学注透学说9、R NAi10、Ubiquitination1、扎糖操纵/和色奴酸操纵/的调控作川2、苏门质结构与功能的关系3、信号转9途径井常9疾病发僅的关系.并设讣种町能的I•扰FBI4、描述〔种不同的组学研丸方法及其任医药学中的嗣IJ5、匕醸辅侑A任物质代谢屮的匝耍作川6、•般1何二DNA损伤对生物体祁是冇害的・”!实质上也右右益的•仏即DNAftl伤仆双咆效应,你如何解释这•观点•。
四川大学·2016年·博士入学英语考试真题与答案解析————————————————————————————————————————完形填空Research on animal intelligence always makes me wonder just how smart humans are. 1 the fruit-fly experiments described in Carl Zimmer’s piece in the Science Times on Tuesday. Fruit flies who were taught to be smarter than the average fruit fly 2 to live shorter lives. This suggests that 3 bulbs burn longer,that there is an 4 in not being too terrifically bright. Intelligence,it 5,is a high-priced option. It takes more upkeep,burns more fuel and is slow 6 the starting line because it depends on learning—a 7 process—instead of instinct. Plenty of other species are able to learn,and one of the things they‘ve apparently learned is when to 8 。
Is there an adaptive value to 9 intelligence?That’s the question behind this new research. I like it. Instead of casting a wistful glance 10 at all the species we ‘ve left in the dust I.Q.-wise,it implicitly asks what the real 11 of our own intelligence might be. This is 12 the mind of every animal I’ve ever met. Research on animal intelligence also makes me wonder what experiments animals would 13 on humans if they had the chance. Every cat with an owner,14 ,is running a small cale study in operant conditioning. We believe that 15 animals ran the labs,they would test us to 16 the limits of our patience,our faithfulness,our memory for terrain. They would try to decide what intelligence in humans is really 17 ,not merely how much of it there is. 18 ,they would hope to study a 19 question:Are humans actually aware of the world they live in?20 the results are inconclusive. 1. [A]Suppose[B]Consider[C]Observe[D]Imagine 2. [A]tended[B]feared[C]happened[D]threatened 3. [A]thinner[B]stabler[C]lighter[D]dimmer 4. [A]tendency[B]advantage[C]inclination[D]priority 5. [A]insists on[B]sums up[C]turns out[D]puts forward 6. [A]off [B]behind[C]over[D]along 7. [A]incredible[B]spontaneous[C]inevitable[D]gradual 8. [A]fight[B]doubt[C]stop[D]think 9. [A]invisible[B]limited[C]indefinite[D]different 10. [A]upward[B]forward[C]afterward[D]backward 11. [A]features[B]influences[C]results[D]costs 12. [A]outside[B]on[C]by[D]across 13. [A]deliver[B]carry[C]perform[D]apply 14. [A]by chance[B]in contrast[C]as usual[D]for instance 15. [A]if[B]unless[C]as[D]lest 16. [A]moderate[B]overcome[C]determine[D]reach 17. [A]at[B]for[C]after[D]with 18. [A]Above all[B]After all[C]However[D]Otherwise 19. [A]fundamental[B]comprehensive[C]equivalent[D]hostile 20. [A]By accident[B]In time[C]So far[D]Better stillI am afraid to sleep. I have been afraid to sleep for the last few weeks. I am so tired that, finally, I do sleep, but only for a few minutes. It is not a bad dream that wakes me ; it is the reality I took with me into sleep . I try to think of something else.Immediately the woman in the marketplace comes into my mind.I was on my way to dinner last night when I saw her . She was selling skirts. She moved with the same ease and loveliness I often saw in the women of Laos. Herlong black hair was as shiny as the black silk of the skirts she was selling . In her hair, she wore three silk ribbons, blue ,green, and white. They reminded me of my childhood and how my girlfriends and I used to spend hours braiding ribbons into our hair.I don’t know the word for “ribbons”, so I put my hand to my own hair and , with three fingers against my head , I looked at her ribbons and said “Beautiful.” She lowered her eyes and said nothing. I wasn’t sure if she understood me (I don’t speak Laotian very well).I looked back down at the skirts. They had designs on them: squares and triangles and circles of pink and green silk. They were very pretty. I decided to buy one of those skirts, and I began to bargain with her over the price. It is the custom to bargain in Asia. In Laos bargaining is done in soft voices and easy moves with the sort of quiet peacefulness.She smiled, more with her eyes than with her lips. She was pleased by the few words I was able to say in her language, although they were mostly numbers, and she saw that I understood something about the soft playfulness of bargaining. We shook our heads in disagreement over the price; then, immediately, we made another offer and then another shake of the head. She was so pleased that unexpectedly, she accepted the last offer I made. But it was too soon. The price was too low. She was being too generous and wouldn’t make enough money. I moved quickly and picked up two more skirts and paid for all three at the price set; that way I was able to pay her three times as much before she had a chance to lower the price for the larger purchase. She smiled openly then, and, for the first time in months, my spirit lifted. I almost felt happy.The feeling stayed with me while she wrapped the skirts in a newspaper and handed them to me. When I left, though, the feeling left, too. It was as though it stayed behind in marketplace. I left tears in my throat. I wanted to cry. I didn’t , ofcourse.I have learned to defend myself against what is hard; without knowing it, I have also learned to defend myself against what is soft and what should be easy.I get up, light a candle and want to look at the skirts. They are still in the newspaper that the woman wrapped them in. I remove the paper, and raise the skirts up to look at them again before I pack them. Something falls to floor. I reach down and feel something cool in my hand. I move close to the candlelight to see what I have. There are five long silk ribbons in my hand, all different colors. The woman in the marketplace! She has given these ribbons to me!There is no defense against a generous spirit, and this time I cry, and very hard, as if I could make up for all the months that I didn’t cry.89. According to the writer, the woman in the marketplace ____B____ .A. refused to speak to her.B. was pleasant and attractive.C. was selling skirts and ribbons.D. recognized her immediately.解析:B。