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Various hematologic abnormalities:Leukocytosis may be high, up until 11,000 leukocytes/mm3, and eosinophilia reaches values higher than 1500/mm3
Hepatitis:hepatomegaly.ALT/AST increased.hepaLeabharlann ic necrosis12
Auxiliary examination
Complete blood count, ALT, AST, total bilirrubin, GGT, alkaline phosphatase, sodium, potassium, creatinine and creatinine clearance, 24h urine protein and urinary eosinophil count, CPK, LDH, ferritin, triglycerides, calcium and PTH, blood glucose,TAP and TTPA, lipase,protein electrophoresis, creactive protein, quantitative PCR for HHV-6, 7, EBV and CMV, blood culture,anti-nuclear factor。
therapy with a limited number of drugs.The cutaneous eruption consists of a morbilliform rash, which is also common in other less severe drug reactions and both presentations are indistinguishable The face, upper trunk and upper extremities are initially affected, with subsequent progression to the lower extremities. Lymphadenopathy (>2mm)