• 逆转免疫抑制状态对于成功治疗至关重要，G-CSF、 GM-CSF、IFN-γ，粒细胞输注、减少或停止使用激素。
Clinical Infectious Diseases 2008; 46:327–60
曲霉菌治疗指南（IDSA08年）
• 手术： Surgical therapy may be useful in patients with lesions that are contiguous with the great vessels or the pericardium, hemoptysis from a single cavitary lesion, or invasion of the chest wall (B-II). Another relative indication for surgery is the resection of a single pulmonary lesion prior to intensive chemotherapy or HSCT (B-II)
米卡芬净（B-II）。 • 在伏立康唑初始治疗失败的侵袭性肺曲霉病患者中不
推荐使用伊曲康唑作为补救治疗。宜选AmB或卡泊芬净。
Clinical Infectious Diseases 2008; 46:327–60
曲霉菌治疗指南（IDSA08年）
• 疗程：至少6-12周；免疫抑制患者需持续整个免疫抑制期， 且病灶吸收。
Clinical Infectious Diseases 2008; 46:1813–21
分级诊断定义的修正（IDSA08年）
• 拟诊（Possible IFD）：The category of possible IFD was retained but was defined more strictly to include only those cases with the appropriate host factors and with sufficient clinical evidence consistent with IFD but for which there was no mycological support
