两种肌酐测定方法性能的比较发表时间：2014-08-14T11:27:32.513Z 来源：《医药前沿》2014年第17期供稿作者：吴进军[导读] 肌酐是肌酸和磷酸肌酸代谢的终产物，它主要由肌肉中磷酸肌酸的非酶促反应生成。
吴进军(湖北江汉油田总医院检验科湖北潜江 432400)【摘要】对测定血肌酐的两种常用方法：苦味酸法和酶法的性能进行分析评估。
方法从准确度、精密度、灵敏度、线性范围及两种试剂测定临床样本的相关性这五个方面进行分析。
结果准确度方面酶法优于苦味酸法。
精密度两种方法学差别不大。
灵敏度和线性范围酶法优于苦味酸法，两种方法临床相关性较好，但酶法测定值要低于苦味酸法。
结论酶法的试剂性能优于苦味酸法，但价钱酶法较高，建议各临床实验室在根据实验室的具体情况选择一个较合适的方法学。
【关键词】肌酐苦味酸法酶法【中图分类号】R446 【文献标识码】A 【文章编号】2095-1752（2014）17-0147-02 Performance comparison of two methods of measuring creatinine WU Jin-jun(Department of Clinical Laboratory，Hubei Jianghan Oilfield General Hospital，Qianjiang，Hubei 432400，China)【Abstract】Objective To analyze the performance of two common methods for measuring serum creatinine: Enzymatic and Jaff’s methods. Methods Performance is analyzed from the following five aspects :accuracy, precision, sensitivity, linearity range and the clinical relevance of the two methods. Results The accuracy of Enzymatic is superior to Jaff’s methods. Precision of the two methods to learn little difference. The sensitivity and linear range of the Enzymatic method is better than Jaff’s method, the clinical relevance of the two methods is good, but the measured value of the Enzymatic method is lower than the Jaff’s method. Conclusion The reagent performance of enzymatic method is better than Jaff’s method, but the enzymatic ‘s prices is higher than Jaff’s method. Clinical laboratory is recommended to select a more appropriate methodology according to the specific circumstances of the laboratory.【Key words】creatinine Jaff’s methods Enzymatic肌酐是肌酸和磷酸肌酸代谢的终产物，它主要由肌肉中磷酸肌酸的非酶促反应生成。
