MSDS29.10.2015 SECTION 1:Identification of the substance/mixture and of the company/undertaking1.1 Product identifiersProduct name :IndoleProduct Number : I3408Brand : AldrichREACH No. : A registration number is not available for this substance as the substanceor its uses are exempted from registration, the annual tonnage does notrequire a registration or the registration is envisaged for a laterregistration deadline.CAS-No. : 120-72-91.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances1.3 Details of the supplier of the safety data sheetCompany : HuBei SiBo Technology Co.,Ltd.FanHu Industrial parkPanJiaWan Town437200 XianNing Hubei,CHINA湖北斯柏生物科技有限公司湖北省咸宁市嘉鱼县潘家湾镇畈湖工业园邮政编码：437200Telephone : +86 0715-*******Fax : +86 0715-*******1.4 Emergency telephone numberEmergency Phone # : +86 0715-*******SECTION 2: Hazards identification2.1 Classification of the substance or mixtureClassification according to Regulation (EC) No 1272/2008Acute toxicity, Oral (Category 4), H302Acute toxicity, Dermal (Category 3), H311Skin irritation (Category 2), H315Serious eye damage (Category 1), H318Specific target organ toxicity - single exposure (Category 3), H335Acute aquatic toxicity (Category 1), H400For the full text of the H-Statements mentioned in this Section, see Section 16. Classification according to EU Directives 67/548/EEC or 1999/45/ECXn, N Harmful, Dangerous for theenvironmentR21/22, R37/38, R41, R50/53For the full text of the R-phrases mentioned in this Section, see Section 16.2.2 Label elementsLabelling according Regulation (EC) No 1272/2008Signal word DangerHazard statement(s)H302 Harmful if swallowed.H311 Toxic in contact with skin.H315 Causes skin irritation.H318 Causes serious eye damage.H335 May cause respiratory irritation.H400 Very toxic to aquatic life.Precautionary statement(s)P261 Avoid breathing dust.P273 Avoid release to the environment.P280 Wear protective gloves/ eye protection/ face protection.P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.P312 Call a POISON CENTER or doctor/ physician if you feel unwell.Supplemental HazardStatementsnone2.3 Other hazardsStench.SECTION 3: Composition/information on ingredients3.1 SubstancesSynonyms : 1H-Benzo[b]pyrroleFormula : C8H7NMolecular Weight : 117,15 g/molCAS-No. : 120-72-9EC-No. : 204-420-7Hazardous ingredients according to Regulation (EC) No 1272/2008Component Classification ConcentrationIndoleAcute Tox. 4; Acute Tox. 3;Skin Irrit. 2; Eye Dam. 1;STOT SE 3; Aquatic Acute 1;H302, H311, H315, H318,H335, H400-Hazardous ingredients according to Directive 1999/45/ECComponent Classification ConcentrationIndoleXn, N, R21/22 - R37/38 - R41- R50/53-For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16SECTION 4: First aid measures4.1 Description of first aid measuresGeneral adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaledIf breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contactWash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.In case of eye contactRinse thoroughly with plenty of water for at least 15 minutes and consult a physician.If swallowedNever give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2) and/or insection 114.3 Indication of any immediate medical attention and special treatment neededno data availableSECTION 5: Firefighting measures5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, alcohol-resistant foam, dry chemical or carbon dioxide.5.2 Special hazards arising from the substance or mixtureCarbon oxides, nitrogen oxides (NOx)5.3 Advice for firefightersWear self contained breathing apparatus for fire fighting if necessary.5.4 Further informationno data availableSECTION 6: Accidental release measures6.1 Personal precautions, protective equipment and emergency proceduresWear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.For personal protection see section 8.6.2 Environmental precautionsPrevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.6.3 Methods and materials for containment and cleaning upPick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.6.4 Reference to other sectionsFor disposal see section 13.SECTION 7: Handling and storage7.1 Precautions for safe handlingAvoid contact with skin and eyes. Avoid formation of dust and aerosols.Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.For precautions see section 2.2.7.2 Conditions for safe storage, including any incompatibilitiesStore in cool place. Keep container tightly closed in a dry and well-ventilated place.Air and light sensitive.7.3 Specific end use(s)A part from the uses mentioned in section 1.2 no other specific uses are stipulatedSECTION 8: Exposure controls/personal protection8.1 Control parametersComponents with workplace control parameters8.2 Exposure controlsAppropriate engineering controlsAvoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.Personal protective equipmentEye/face protectionFace shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).Skin protectionHandle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC andthe standard EN 374 derived from it.Full contactMaterial: Nitrile rubberMinimum layer thickness: 0,11 mmBreak through time: 480 minMaterial tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)Splash contactMaterial: Nitrile rubberMinimum layer thickness: 0,11 mmBreak through time: 480 minMaterial tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)datasource:KCLGmbH,D-36124Eichenzell,phone+49(0)665987300,******************,test method: EN374If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and mustbe evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.Body ProtectionComplete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protectionWhere risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards suchas NIOSH (US) or CEN (EU).Control of environmental exposurePrevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.SECTION 9: Physical and chemical properties9.1 Information on basic physical and chemical propertiesa) Appearance Form: flakesColour: light brownb) Odour no data availablec) Odour Threshold no data availabled) pH no data availablee) Melting point/freezingpointMelting point/range: 51 - 54 °C - lit.f) Initial boiling point andboiling range253 - 254 °C - lit.g) Flash point 121 °C - closed cuph) Evapouration rate no data availablei) Flammability (solid, gas) no data availablej) Upper/lowerflammability orexplosive limitsno data availablek) Vapour pressure no data availablel) Vapour density no data availablem) Relative density no data availablen) Water solubility no data availableo) Partition coefficient: noctanol/waterno data availablep) Auto-ignitiontemperatureno data availableq) Decompositiontemperatureno data availabler) Viscosity no data availables) Explosive properties no data availablet) Oxidizing properties no data available9.2 Other safety informationno data availableSECTION 10: Stability and reactivity 10.1 Reactivityno data available10.2 Chemical stabilityStable under recommended storage conditions. 10.3 Possibility of hazardous reactions no data available10.4 Conditions to avoidAir Light.10.5 Incompatible materialsStrong oxidizing agents, Iron and iron salts.10.6 Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5SECTION 11: Toxicological information11.1 Information on toxicological effectsAcute toxicityLD50 Oral - rat - 1.000 mg/kgLD50 Dermal - rabbit - 790 mg/kgSkin corrosion/irritationSerious eye damage/eye irritationEyes - rabbitResult: Severe eye irritation - 24 hRespiratory or skin sensitisationno data availableGerm cell mutagenicityno data availableCarcinogenicityCarcinogenicity - mouse - SubcutaneousTumorigenic:Equivocal tumorigenic agent by RTECS criteria. Lungs, Thorax, or Respiration:Tumors. LeukaemiaCarcinogenicity - mouse - SubcutaneousTumorigenic:Equivocal tumorigenic agent by RTECS criteria. Tumorigenic:Tumor types after systemic administration not seen spontaneously.IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.Reproductive toxicityno data availableSpecific target organ toxicity - single exposureInhalation - May cause respiratory irritation.Specific target organ toxicity - repeated exposureno data availableAspiration hazardno data availableAdditional InformationRTECS: NL2450000Nausea, Headache, V omiting, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.SECTION 12: Ecological information12.1 ToxicityToxicity to daphnia andother aquaticinvertebratesLC50 - Daphnia magna (Water flea) - 1 mg/l - 48 hToxicity to algae Growth inhibition EC100 - Scenedesmus acuminatus - > 10 mg/l - 96 h12.2 Persistence and degradabilityno data available12.3 Bioaccumulative potentialno data available12.4 Mobility in soilno data available12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment not available as chemical safety assessment not required/not conducted 12.6 Other adverse effectsVery toxic to aquatic life.SECTION 13: Disposal considerations13.1 Waste treatment methodsProductOffer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packagingDispose of as unused product.SECTION 14: Transport information14.1 UN numberADR/RID: 2811 IMDG: 2811 IATA: 281114.2 UN proper shipping nameADR/RID: TOXIC SOLID, ORGANIC, N.O.S. (Indole)IMDG: TOXIC SOLID, ORGANIC, N.O.S. (Indole)IATA: Toxic solid, organic, n.o.s. (Indole)14.3 Transport hazard class(es)ADR/RID: 6.1 IMDG: 6.1 IATA: 6.114.4 Packaging groupADR/RID: III IMDG: III IATA: III14.5 Environmental hazardsADR/RID: yes IMDG Marine pollutant: yes IATA: no14.6 Special precautions for userno data availableSECTION 15: Regulatory informationThis safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.15.1 Safety, health and environmental regulations/legislation specific for the substance or mixtureno data available15.2 Chemical Safety AssessmentFor this product a chemical safety assessment was not carried outSECTION 16: Other informationFull text of H-Statements referred to under sections 2 and 3.Acute Tox. Acute toxicityAquatic Acute Acute aquatic toxicityEye Dam. Serious eye damageH302 Harmful if swallowed.H311 Toxic in contact with skin.H315 Causes skin irritation.H318 Causes serious eye damage.H335 May cause respiratory irritation.H400 Very toxic to aquatic life.Skin Irrit. Skin irritationSTOT SE Specific target organ toxicity - single exposureFull text of R-phrases referred to under sections 2 and 3N Dangerous for the environmentXn HarmfulR21/22 Harmful in contact with skin and if swallowed.R37/38 Irritating to respiratory system and skin.R41 Risk of serious damage to eyes.R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.。
