Q-VD-OPh-SDS-MedChemExpress

名称类型功能反应物GSH过氧化物酶氧化谷胱甘肽的还原作用谷胱甘肽(GSH)、H2O2 GSH还原酶还原谷胱甘肽的还原作用G SSG己糖激酶磷酸化糖酵解途径葡萄糖、ATP葡萄糖激酶磷酸化糖酵解途径葡萄糖、ATP磷酸己糖异构酶异构糖酵解途径6-磷酸葡萄糖6-磷酸果糖激酶-1磷酸化糖酵解途径6-磷酸果糖醛缩酶裂解糖酵解途径1,6-二磷酸果糖磷酸丙糖异构酶异构糖酵解途径磷酸二羟丙酮3-磷酸甘油醛脱氢酶底磷化糖酵解途径3-磷酸甘油醛、Pi磷酸甘油酸激酶底磷化糖酵解途径1,3-二磷酸甘油酸、ADP磷酸甘油酸变位酶异构糖酵解途径3-磷酸甘油酸烯醇化酶脱水糖酵解途径2-磷酸甘油酸丙酮酸激酶脱磷酸糖酵解途径磷酸烯醇式丙酮酸、ADP乳酸脱氢酶（LDHⅠ）加氢糖酵解丙酮酸乳酸脱氢酶（LDHⅤ）脱氢糖异生乳酸6-磷酸果糖激酶-2磷酸化糖酵解调节6-磷酸果糖、ATP果糖二磷酸酶-2脱磷酸糖酵解调节2,6-二磷酸果糖、H2O丙酮酸脱氢酶（E1）脱氢丙酮酸氧化脱羧丙酮酸、TPP二氢硫辛酸转乙酰酶（E2）转乙酰丙酮酸氧化脱羧羟乙基TPP、硫辛酸、CoASH 二氢硫辛酸脱氢酶脱氢丙酮酸氧化脱羧二氢硫辛酸柠檬酸合酶转羧基三羧酸循环草酰乙酸、乙酰CoA、H2O 顺乌头酸酶异构三羧酸循环柠檬酸异柠檬酸脱氢酶氧化脱羧三羧酸循环异柠檬酸α-酮戊二酸脱氢酶（复合体）氧化脱羧三羧酸循环α-酮戊二酸、CoASH琥珀酰CoA合成酶（琥珀酸硫激酶）底磷化三羧酸循环琥珀酰CoA、GDP、Pi琥珀酸脱氢酶脱氢三羧酸循环琥珀酸延胡索酸酶加水三羧酸循环延胡索酸、H2O苹果酸脱氢酶脱氢三羧酸循环苹果酸6-磷酸葡萄糖脱氢酶脱氢磷酸戊糖途径6-磷酸葡萄糖6-磷酸葡萄糖酸δ内酯酶（内酯酶）水解磷酸戊糖途径6-磷酸葡萄糖内酯、H2O6-磷酸葡萄糖酸脱氢酶脱氢磷酸戊糖途径6-磷酸葡萄糖酸（异构酶）异构磷酸戊糖途径5-磷酸核酮糖丙酮酸羧化酶羧化糖异生途径丙酮酸、ATP、CO2磷酸烯醇式丙酮羧激酶羧化糖异生途径草酰乙酸、GTP谷草转氨酶转氨基糖异生草酰乙酸，谷氨酸果糖二磷酸酶-1脱磷酸糖异生途径1,6-二磷酸果糖、H2O葡萄糖-6-磷酸酶水解糖异生途径6-磷酸葡萄糖、H2O磷酸葡萄糖变位酶异构糖原合成6-磷酸葡萄糖UDPG焦磷酸化酶水解糖原合成1-磷酸葡萄糖、UTP糖原合成酶（误：糖原合酶）合成糖原合成糖原分支酶异构糖原合成糖原糖原磷酸化酶水解糖原分解糖原脱支酶1（葡萄糖转移酶）异构糖原分解糖原（分支）脱支酶2（α-1,6-葡萄糖苷酶）水解糖原分解糖原ALA合酶转酰基血红素合成琥珀酰CoA、甘氨酸ALA脱水酶脱水缩合血红素合成ALA卟胆原脱氨酶脱氨血红素合成卟胆原（PBG）尿卟啉原Ⅲ同合酶脱氨血红素合成线状四吡咯尿卟啉原Ⅲ脱羧酶脱羧血红素合成尿卟啉原Ⅲ粪卟啉原Ⅲ氧化脱羧酶氧化脱羧血红素合成粪卟啉原Ⅲ原卟啉原Ⅸ氧化酶氧化血红素合成原卟啉原Ⅸ亚铁螯合酶结合血红素合成原卟啉Ⅸ二磷酸甘油酸变位酶异构2,3-BPG支路1,3-二磷酸甘油酸二磷酸甘油酸磷酸酶水解2,3-BPG支路2,3-BPG(2,3-二磷酸甘油酸)、复合体Ⅰ：NADH-Q还原酶脱电子呼吸链NADH、H+、CoQ复合体Ⅱ：琥珀酸-Q还原酶脱电子呼吸链FADH2、CoQ复合体Ⅲ：细胞色素还原酶脱电子呼吸链QH2，细胞色素c复合体Ⅳ：细胞色素氧化酶脱电子呼吸链还原性细胞色素c、氧原子ATP合成酶（ATP合酶）磷酸化呼吸链ADP、Piα-磷酸甘油脱氢酶加氢α-磷酸甘油穿梭磷酸二羟丙酮、H+α-磷酸甘油脱氢酶*脱氢α-磷酸甘油穿梭α-磷酸甘油、CoQ过氧化氢酶氧化线粒体外氧化体系H2O2过氧化物酶氧化线粒体外氧化体系H2O2、R超氧化物歧化酶（SOD）氧化线粒体外氧化体系H+、O2-胰脂酶水解脂类的消化三酰甘油、H2O磷脂酶A2水解脂类的消化磷脂、H2O胆固醇酯酶水解脂类的消化胆固醇酯脂酰CoA合成酶转酰基甘油一酯途径脂肪酸、CoASH、ATP脂酰CoA转移酶转酰基甘油一酯途径2-单酰甘油、脂酰CoA三酰甘油脂肪酶水解脂肪动员三酰甘油、H2O二酰甘油脂肪酶水解脂肪动员二酰甘油、H2O单酰甘油脂肪酶水解脂肪动员单酰甘油、H2O脂酰CoA合成酶*转酰基脂肪酸β-氧化脂肪酸、CoASH、ATP肉碱脂酰转移酶Ⅰ转酰基脂肪酸β-氧化脂酰CoA、肉碱肉碱-脂酰肉碱转位酶转酰基?脂肪酸β-氧化脂酰肉碱（外）、肉碱（内）肉碱脂酰转移酶Ⅱ转酰基脂肪酸β-氧化CoASH、脂酰肉碱脂酰CoA脱氢酶脱氢脂肪酸β-氧化脂酰CoA（C n+2)烯脂酰CoA水合酶加水脂肪酸β-氧化反式⊿2-烯脂酰CoA、H2Oβ-羟脂酰脱氢酶脱氢脂肪酸β-氧化L(+)-β-羟脂酰CoA（β-酮脂酰）硫解酶硫解脂肪酸β-氧化β-酮脂酰CoA、CoASH丙酰CoA羧化酶等羧化、异构奇碳脂肪酸氧化丙酰CoA、CO2、ATP乙酰乙酰CoA硫解酶转酰基酮体生成乙酰CoAHMG-CoA合酶缩合酮体生成乙酰乙酰CoA、乙酰CoA、H2O HMG-CoA裂解酶分解酮体生成HMG-CoAβ-羟基丁酸脱氢酶加氢酮体生成乙酰乙酸β-羟基丁酸脱氢酶*脱氢酮体氧化β-羟基丁酸琥珀酰CoA转硫酶转酰基酮体氧化乙酰乙酸、琥珀酰CoA乙酰乙酸硫激酶转酰基酮体氧化乙酰乙酸、CoASH、ATP乙酰乙酰CoA硫解酶*转酰基酮体氧化乙酰乙酰CoA、CoASH甘油磷酸激酶磷酸化甘油氧化分解甘油、ATP磷酸甘油脱氢酶脱氢甘油氧化分解3-磷酸甘油柠檬酸裂解酶转酰基柠檬酸-丙酮酸循环柠檬酸、CoASH、ATP苹果酸酶脱羧柠檬酸-丙酮酸循环苹果酸乙酰CoA羧化酶羧化脂肪酸合成乙酰CoA、ATP、CO2、H2O乙酰基转移酶转酰基脂肪酸合成乙酰CoA、（β-酮脂酰合酶）丙二酰转移酶转酰基脂肪酸合成乙酰-酶复合物、丙二酰CoAβ-酮脂酰合酶脱羧脂肪酸合成乙酰-丙二酰-酶复合物β-酮脂酰还原酶加氢脂肪酸合成β-酮脂酰～S-ACPβ-羟脂酰脱水酶（水合酶）脱水脂肪酸合成β-羟基丁酰～S-ACPΔ2-烯脂酰还原酶加氢脂肪酸合成Δ2-烯脂酰～S-ACP长链脂酰硫酯酶水解脂肪酸合成软脂酰～S-ACP、H2O脂肪酸合成酶系合成脂肪酸合成乙酰CoA、丙二酰CoA、ATP、C （人）脂肪酸去饱和酶脱氢不饱和脂酸合成饱和脂肪酸脂酰CoA转移酶*转酰基甘油二酯途径3-磷酸甘油、脂酰CoA磷脂酸磷脂酶脱磷酸甘油二酯途径磷脂酸脂酰CoA转移酶*2转酰基甘油二酯途径1,2-甘油二酯、脂酰CoA CTP：磷酸乙醇胺胞苷转移酶转苷甘油二酯合成途径磷酸乙醇胺、CTPCTP：磷酸胆碱胞苷转移酶转苷甘油二酯合成途径磷酸胆碱、CTP（转移酶）转苷甘油二酯合成途径1,2-甘油二酯、CDP-磷酸乙醇（转移酶）*转苷甘油二酯合成途径1,2-甘油二酯、CDP-磷酸乙醇心磷脂合成酶转苷CDP-甘油二酯合成途C DP-甘油二酯、磷脂酰甘油磷脂酰肌醇合成酶转苷CDP-甘油二酯合成途C DP-甘油二酯、磷脂酰肌醇乙酰乙酰CoA硫解酶*转酰基甲羟戊酸途径乙酰CoAHMG-CoA合酶*缩合甲羟戊酸途径乙酰乙酰CoA、乙酰CoA、H2O甲羟戊酸途径HMG-CoAHMG-CoA还原酶加氢、脱酰基胆固醇合成甲羟戊酸（鲨烯合成酶系）Ⅰ磷酸化、脱羧（鲨烯合成酶系）Ⅱ异构、缩合胆固醇合成异戊烯焦磷酸（5C）胆固醇合成鲨烯（30C）（形成胆固醇酶系）环化、脱羧等脂酰CoA胆固醇脂酰转移酶（ACAT）转酰基胆固醇酯化胆固醇、脂酰CoA卵磷脂胆固醇脂酰转移酶（LCAT）转酰基胆固醇酯化胆固醇、卵磷脂脂蛋白脂肪酶水解血浆脂蛋白代谢CM\VLDL肝脂肪酶水解血浆脂蛋白代谢CM残粒\VLDL残粒加单氧酶系氧化肝的生物转化ⅠRH、O2单胺氧化酶系氧化肝的生物转化Ⅰ胺、O2、H2O脱氢酶系：肝细胞醇脱氢酶氧化肝的生物转化Ⅰ乙醇脱氢酶系：醛脱氢酶氧化肝的生物转化Ⅰ乙醛硝基还原酶还原肝的生物转化Ⅰ硝基化合物偶氮还原酶还原肝的生物转化Ⅰ偶氮化合物水解酶系水解肝的生物转化Ⅰ酯类\酰胺类\糖苷类化合物、UDP-葡萄糖醛酸转移酶转酰基肝的生物转化Ⅱ醇\酚\胺\羧酸类化合物、UDP 硫酸转移酶转酰基肝的生物转化Ⅱ类固醇\酚\胺\芳香胺类化合物谷胱甘肽S-转移酶转酰基肝的生物转化Ⅱ芳香卤类\烷烃基\硝基化合物乙酰转移酶转酰基肝的生物转化Ⅱ芳香胺类化合物、乙酰CoA氨基酸N-酰基转移酶转酰基肝的生物转化Ⅱ自由羧基化合物、乙酰CoA甲基转移酶转酰基肝的生物转化Ⅱ羟基\硫基\氨基化合物、SAM 7α-羟化酶羟化游离胆汁酸生成胆固醇、O2微粒体血红素加氧酶加氧胆红素生成血红素、O2胆绿素还原酶加氢胆红素生成胆绿素UDP-葡萄糖醛酸转移酶*转酰基结合胆红素生成胆红素、UDPGA（肠菌酶）脱离胆素生成胆红素葡萄糖醛酸酯磷酸核糖焦磷酸激酶磷酸化PRPP的生成5-磷酸核糖、ATPIMP的合成PRPP、谷氨酰胺、H2OPRPP酰胺转移酶脱磷酸、转酰GAR合成酶缩合IMP的合成5-PRA、甘氨酸、ATPGAR甲酰转移酶转酰基IMP的合成GAR、N10-甲酰FH4FGAM合成酶亚氨基化IMP的合成FGAR、谷氨酰胺、ATPAIR合成酶环化IMP的合成FGAM、ATPAIR羧化酶羧化IMP的合成AIR、CO2、ATPSAICAR合成酶缩合IMP的合成CAIR、天冬氨酸、ATP SAICAR裂解酶水解IMP的合成SAICAR、H2OAICAR甲酰转移酶转酰基IMP的合成AICAR、N10-甲酰FH4次黄嘌呤核苷酸合成酶环化IMP的合成FAICAR腺苷酸代琥珀酸合成酶缩合AMP的合成IMP、天冬氨酸、GTP腺苷酸代琥珀酸裂解酶水解AMP的合成腺苷酸代琥珀酸、H2OIMP脱氢酶脱氢GMP的合成IMP、H2OGMP合成酶亚氨基化GMP的合成XMP、谷氨酰胺、ATP（激酶）磷酸化NTP的生成NMP\dNMP、Pi腺嘌呤磷酸核糖转移酶（APRT）转移嘌呤核苷酸补救合成腺嘌呤、PRPP次黄嘌呤-鸟嘌呤磷酸核糖转移酶（HG转移嘌呤核苷酸补救合成次黄嘌呤\鸟嘌呤、PRPP腺苷激酶磷酸化嘌呤核苷酸补救合成腺苷、ATP核苷酸酶脱磷酸嘌呤核苷酸降解AMP\GMP核苷脱氨酶脱氨嘌呤核苷酸降解腺苷嘌呤核苷酸降解次黄苷\鸟苷、Pi嘌呤核苷磷酸化酶磷酸化、水解黄嘌呤氧化酶氧化嘌呤核苷酸降解次黄嘌呤、O2、H2O鸟嘌呤脱氨酶脱氨嘌呤核苷酸降解鸟嘌呤、H2O黄嘌呤氧化酶*氧化嘌呤核苷酸降解黄嘌呤、O2、H2O氨基甲酰磷酸合成酶Ⅱ（CPSⅡ）缩合、磷酸化UMP的合成ATP、CO2、H2O、谷氨酰胺UMP的合成氨基甲酰磷酸、天冬氨酸天冬氨酸氨基甲酰转移酶（ATCase）脱磷酸、缩合二氢乳清酸酶环化UMP的合成氨基酰天冬氨酸二氢乳清酸脱氢酶脱氢UMP的合成二氢乳清酸嘧啶磷酸核糖转移酶转移UMP的合成乳清酸、PRPPOMP脱羧酶脱羧UMP的合成乳清酸核苷酸（OMP）CTP合成酶氨基化CTP的合成UTP、谷氨酰胺、ATP嘧啶磷酸核糖转移酶*转移嘧啶核苷酸补救合成嘧啶、PRPP尿苷激酶磷酸化嘧啶核苷酸补救合成尿嘧啶核苷、ATP（脱氨基酶）脱氨嘧啶核苷酸分解代谢胞嘧啶、H2O嘧啶核苷酸分解代谢尿嘧啶、H2O尿嘧啶分解酶系加氢、开环、嘧啶核苷酸分解代谢胸腺嘧啶、H2O胸腺嘧啶分解酶系加氢、开环、核糖核苷酸还原酶还原脱氧核苷酸的生成NDP、还原型硫氧还蛋白硫氧还蛋白还原酶还原脱氧核苷酸的生成氧化型硫氧还蛋白γ-谷氨酰基转移酶转酰基γ-谷氨酰基循环谷胱甘肽(GSH)、氨基酸γ-谷氨酸环化转移酶水解、环化γ-谷氨酰基循环γ-谷氨酰氨基酸5-氧脯氨酸酶水解γ-谷氨酰基循环5-氧脯氨酸、ATP（肽酶）水解γ-谷氨酰基循环半胱氨酰甘氨酸γ-谷氨酰半胱氨酸合成酶合成γ-谷氨酰基循环半胱氨酸、谷氨酸、ATP谷胱甘肽合成酶合成γ-谷氨酰基循环γ-谷氨酰半胱氨酸、甘氨酸、ATP 泛素活化酶转酰基泛素介导的蛋白质降泛素、泛素活化酶、ATP泛素-泛素活化酶转酰基泛素介导的蛋白质降泛素-泛素活化酶、泛素载体蛋泛素-蛋白连接酶转酰基泛素介导的蛋白质降蛋白质、泛素-泛素载体蛋白丙氨酸氨基转移酶（ALT）转氨基转氨基作用谷氨酸、丙酮酸心肌天冬氨酸氨基转移酶（AST）转氨基转氨基作用谷氨酸、草酰乙酸L-谷氨酸脱氢酶脱氢、脱氨氧化脱氨基作用L-谷氨酸、H2O谷氨酰胺合成酶氨基化氨的储存和运输NH3、谷氨酸谷氨酰胺酶脱氨氨的储存和运输谷氨酰胺氨基甲酰磷酸合成酶Ⅰ（CPSⅠ）合成尿素合成H2O、CO2、NH3、ATP鸟氨酸氨基甲酰转移酶（OCT）转酰基尿素合成鸟氨酸、氨基甲酰磷酸精氨酸代琥珀酸合成酶（ASS）缩合尿素合成瓜氨酸、天冬氨酸、ATP精氨酸代琥珀酸裂解酶（ASL）裂解尿素合成精氨酸代琥珀酸精氨酸酶水解尿素合成精氨酸、H2O（氨基酸脱羧酶）脱羧氨基酸脱羧基作用氨基酸L-谷氨酸脱羧酶脱羧氨基酸脱羧基作用L-谷氨酸磺酸丙氨酸脱羧酶脱羧氨基酸脱羧基作用磺酸丙氨酸组氨酸脱羧酶脱羧氨基酸脱羧基作用L-组氨酸色氨酸羟化酶羟化氨基酸脱羧基作用色氨酸5-羟色胺酸脱羧酶脱羧氨基酸脱羧基作用5-羟色氨酸鸟氨酸脱羧酶脱羧氨基酸脱羧基作用鸟氨酸SAM脱羧酶脱羧氨基酸脱羧基作用S-腺苷甲硫氨酸（SAM）氨丙基转移酶转移氨基酸脱羧基作用腐胺、脱羧基SAM氨丙基转移酶*转移氨基酸脱羧基作用亚精胺（精脒）、脱羧基SAM 二氢叶酸合成酶合成一碳单位代谢二氢蝶呤啶、对氨基苯甲酸、二氢叶酸还原酶还原一碳单位代谢FH2、[H]?腺苷转移酶转移含硫氨基酸代谢蛋氨酸、ATP甲基转移酶转甲基含硫氨基酸代谢S-腺苷甲硫氨酸（SAM）、甲基腺苷同型半胱氨酸酶水解含硫氨基酸代谢S-腺苷同型半胱氨酸、H2O甲基转移酶*转甲基含硫氨基酸代谢同型半胱氨酸、甲基FH4脒基转移酶转移肌酸和磷酸肌酸代谢精氨酸、甘氨酸甲基转移酶*2转甲基肌酸和磷酸肌酸代谢胍乙酸、S-腺苷甲硫氨酸（SA 肌酸激酶（CK）磷酸化肌酸和磷酸肌酸代谢肌酸、ATP（肌酸环化酶）环化肌酸和磷酸肌酸代谢肌酸（磷酸肌酸脱磷酸酶）脱磷酸肌酸和磷酸肌酸代谢磷酸肌酸苯丙氨酸羟化酶羟化芳香族氨基酸代谢苯丙氨酸、O2、FH4苯丙氨酸转氨酶转氨基芳香族氨基酸代谢苯丙氨酸酪氨酸羟化酶羟化芳香族氨基酸代谢酪氨酸酪氨酸酶羟化芳香族氨基酸代谢酪氨酸酪氨酸转氨酶转氨基芳香族氨基酸代谢酪氨酸（支链氨基酸转氨酶）转氨基支链氨基酸代谢（缬氨酸、亮氨酸、异亮氨酸生成物辅酶/辅基激活剂抑制剂GSSG、H2OGSH NADP+6-磷酸葡萄糖、ADP Mg2+6-磷酸果糖6-磷酸葡萄糖、ADP Mg2+6-磷酸果糖6-磷酸果糖Mg2+1,6-二磷酸果糖Mg2+AMP、ADP、F-6-P、F柠檬酸、ATP磷酸二羟丙酮、3-磷酸甘油醛3-磷酸甘油醛1,3-二磷酸甘油酸NAD+3-磷酸甘油酸、ATP Mg2+2-磷酸甘油酸Mg2+磷酸烯醇式丙酮酸、H2O丙酮酸、ATP K+、Mg2+1,6-二磷酸果糖丙氨酸、高ATP水平乳酸NADH、H+丙酮酸NAD+2,6-二磷酸果糖、ADP6-磷酸果糖、Pi羟乙基TPP焦磷酸硫胺素（TPP）乙酰CoA、二氢硫辛酸二氢硫辛酸、辅酶A硫辛酸FAD（直接）、NAD+柠檬酸、CoASH ADP ATP、柠檬酸、NADH、琥珀酰CoA 异柠檬酸α-酮戊二酸、CO2NAD+ADP、Ca2+ATP琥珀酰CoA、CO2NAD+、硫辛酸、FAD、TPP乙酰CoA、琥珀酰CoA、NAD琥珀酸、CoASH、GTP延胡索酸FAD丙二酸苹果酸草酰乙酸NAD+6-磷酸葡萄糖内酯NADP+NADPH6-磷酸葡萄糖酸5-磷酸核酮糖、CO2NADP+5-磷酸核糖草酰乙酸、ADP+Pi生物素磷酸烯醇式丙酮酸、GDP、CO2天冬氨酸，α-酮戊二酸6-磷酸果糖、Pi葡萄糖、Pi1-磷酸葡萄糖UDPG、PPi糖原（+1）ATP、6-P-G糖原（分支）糖原（-1）AMP，Ca+ATP、6-P-G、葡萄糖糖原糖原（脱支）ALA、CO2、CoASH磷酸吡哆醛（维生素B6）血红素/高铁血红素Pb卟胆原（PBG）线状四吡咯、NH3尿卟啉原Ⅲ、NH3粪卟啉原Ⅲ、CO2原卟啉原Ⅸ原卟啉Ⅸ血红素Pb2,3-BPG(2,3-二磷酸甘油酸)3-磷酸甘油酸、PiQH2、NAD+FMN、Fe-S鱼藤酮、安密妥、粉蝶酶素QH2、FAD FAD、Fe-SCoQ、还原性细胞色素c血红素b-562、血红素b-566、血红素c1、Fe-S抗霉素A、二巯基丙醇细胞色素c、H2O血红素a、血红素a3、CuA和CuB CO、CN-、叠氮化物ATP ADP（主要），甲状腺素α-磷酸甘油NADH、H+磷酸二羟丙酮、QH2FAD、Fe-SH2O、O2H2O、ROH2O2、O22-单酰甘油、游离脂肪辅脂酶溶血磷脂、游离脂肪酸（FFA）胆固醇、游离脂肪酸（FFA）脂酰CoA、AMP、PPi三酰甘油、CoASH三酰甘油、游离脂肪酸（FFA）肾上腺素、胰高血糖胰岛素单酰甘油、游离脂肪酸（FFA）甘油、游离脂肪酸（FFA）脂酰CoA、AMP、PPiCoASH、脂酰肉碱脂酰肉碱（内）、肉碱（外）脂酰CoA、肉碱反式⊿2-烯脂酰CoA FADL(+)-β-羟脂酰CoAβ-酮脂酰CoA NAD+脂酰CoA（C n)、乙酰CoA琥珀酰CoA、ADP、Pi乙酰乙酰CoA、CoASHHMG-CoA乙酰乙酸、乙酰CoAβ-羟基丁酸NADH、H+乙酰乙酸NAD+乙酰乙酰CoA、琥珀酸乙酰乙酰CoA、AMP、PPi乙酰CoA3-磷酸甘油、ADP磷酸二羟丙酮NAD草酰乙酸、乙酰CoA、ADP、Pi丙酮酸丙二酰CoA、ADP、Pi生物素、Mn2+柠檬酸、异柠檬酸、长链脂酰CoA、胰高血糖素乙酰-酶复合物、CoASH乙酰-丙二酰-酶复合物、CoASHβ-酮脂酰～S-ACP、CO2β-羟基丁酰～S-ACPNADPH、H+Δ2-烯脂酰～S-ACP、H20丁酰～S-ACP NADPH、H+软脂酸、（β-酮脂酰合酶）软脂酸、CO2、H2O、AD NADPH、H+单不饱和脂肪酸磷脂酸、CoASH1,2-甘油二酯、Pi三酰甘油、CoASHCDP-磷酸乙醇胺、PPiCDP-磷酸胆碱、PPi脑磷脂、CMP卵磷脂、CMP心磷脂、CMP磷脂酰肌醇、CMP乙酰乙酰CoA、CoASHHMG-CoA甲羟戊酸、CoASH NADPH、H+胰岛素、甲状腺素、胰高血糖素异戊烯焦磷酸鲨烯（30C）胆固醇、CO2胆固醇酯胆固醇酯、溶血卵磷脂CM残粒\VLDL残粒甘油、FFA、溶血磷脂等ROH、H2O NADPH、H+醛、NH3、H2O2乙醛乙酸氨基化合物二氢偶氮化合物（裂解）（产物）（产物）、UDP（产物）、PAP（产物）、CoASH（产物）、CoASH（谷胱甘肽结合产物）（产物）、S-腺苷同型半胱氨酸7α-羟胆固醇NADPH、H+维生素C、甲状腺素胆绿素、CO、Fe3+NADPH、H+血红素胆红素NADPH、H+胆红素葡萄糖醛酸酯、UDP胆红素、（葡萄糖醛酸）PRPP、AMP ADP5-PRA、谷氨酸、PPi Mg2+ATP、PRPP AMP、ADP、别嘌呤醇、6-巯GAR、ATP、Pi Mg2+FGAR、FH4FGAM、谷氨酸、ADP、PiAIR、ADP、Pi Mg2+CAIR、ADP、Pi生物素SAICAR、ADP、PiAICAR、延胡索酸FAICAR、FH4IMP、H2O腺苷酸代琥珀酸、GDP、Pi GTP AMP、6-巯基嘌呤AMP、延胡索酸GTP AMPXMP NAD+ATP GMP、6-巯基嘌呤GMP、谷氨酸、ADP、Pi ATP GMPNTP\dNTPATP、PPiITP\UTP、Ppi6-巯基嘌呤AMP、ADP腺苷\鸟苷次黄苷次黄嘌呤\鸟嘌呤、5-磷酸核糖黄嘌呤、H2O2黄嘌呤、NH3尿酸、H2O2氨基甲酰磷酸、ADP、Pi、谷氨酸PRPP、ATP UMP氨基酰天冬氨酸、Pi ATP氨基酰天冬氨酸、CTP 二氢乳清酸、H2O乳清酸NAD+乳清酸核苷酸PRPPUMP、CO2CTP、谷氨酸、ADP、Pi嘧啶核苷酸、PpiUMP、ADP尿嘧啶、NH3β-丙氨酸、NH3、CO2N ADPH\NADH、H+NADPH\NADH、H+β-氨基异丁酸、NH3、CO2dNDP、H2O、氧化型硫氧还蛋白还原型硫氧还蛋白NADPH、H+γ-谷氨酰氨基酸、半胱氨酰甘氨酸氨基酸、5-氧脯氨酸谷氨酸、ADP、Pi甘氨酸、半胱氨酸γ-谷氨酰半胱氨酸、ADP、Pi谷胱甘肽、ADP、Pi泛素-泛素活化酶、AMP、Ppi泛素-泛素活化酶、泛素活化酶泛素-蛋白质α-酮戊二酸、丙氨酸磷酸吡哆醛（维生素B6）磷酸吡哆醛（维生素B6）α-酮戊二酸、天冬氨酸α-酮戊二酸、NH3NADPH\NADH、H+GDP、ADP GTP、ATP谷氨酰胺NH3、谷氨酸氨基甲酰磷酸、ADP、P Mg2+N-乙酰谷氨酸（AGA）瓜氨酸、Pi（磷酸形式）精氨酸代琥珀酸、H2O、AMP、PPi精氨酸、延胡索酸尿素、鸟氨酸胺类、CO2GABA、CO2牛磺酸、CO2组胺、CO25-羟色氨酸5-羟色胺、CO2腐胺、CO2脱羧基SAM、CO2亚精胺（精脒）、5'-甲基-S-腺苷精胺FH2磺胺类药物FH4氨甲蝶呤S-腺苷甲硫氨酸（SAM）、PPi、PiS-腺苷同型半胱氨酸、甲基化产物同型半胱氨酸、腺苷蛋氨酸、FH4鸟氨酸、胍乙酸肌酸、S-腺苷同型半胱氨酸磷酸肌酸、ADP肌酐、H2O肌酐、Pi酪氨酸、H2O、FH2苯丙酮酸多巴（3,4-二羟苯丙氨酸）多巴（3,4-二羟苯丙氨C u2+羟苯丙酮酸相应的脂酰CoA调节方式其他其他Ⅱ激素调节，变构调节关键酶Ⅰ、Ⅱ、Ⅲ广泛，同工酶，胰岛素，产物的反馈抑制激素调节，变构调节，共关键酶Ⅳ肝，胰岛素，同工酶激素调节关键酶胰岛素底物水平磷酸化底物水平磷酸化激素调节关键酶胰高血糖素使酶失活同工酶5种同工酶同工酶产物激活6-磷酸果糖激酶-2变构调节，化学修饰丙酮酸脱氢酶复合体、含维生素B1变构调节，化学修饰丙酮酸脱氢酶复合体、含硫辛酸、泛酸变构调节，化学修饰丙酮酸脱氢酶复合体、含维生素B2、PP、NADH、琥珀酰CoA关键酶柠檬酸-丙酮酸循环中间产物顺乌头酸、H2O关键酶第一次氧化脱羧变构调节，化学修饰关键酶第二次氧化脱羧底物水平磷酸化竞争性抑制反向进行可使草酰乙酸穿出线粒体膜反馈抑制关键酶主要受NADPH/NADP+比值调节不可逆不可逆包括磷酸戊糖异构酶和磷酸戊糖差向酶激素调节，反馈抑制关键酶线粒体激素调节，反馈抑制关键酶线粒体/胞液另：苹果酸/天冬氨酸穿梭（肝和心肌）激素调节，反馈抑制关键酶激素调节，反馈抑制关键酶反向进行可将1-P-G转化为6-P-G葡萄糖活化共价修饰，变构调节关键酶作用于α-1,4糖苷键，肾上腺素/胰高血糖素抑制作用于α-1,6糖苷键共价修饰，变构调节关键酶作用于α-1,4糖苷键，至距分支4个残基处，肾上腺素/胰高血糖素促进至距分支1个残基处作用于α-1,6糖苷键激素调节，反馈抑制限速酶ALA（δ-氨基-γ-酮戊酸），缺氧，雄激素和睾酮标志酶密妥、粉蝶酶素完全镶嵌在线粒体内膜中，有质子泵功能线粒体内膜基质侧，无质子泵功能完全镶嵌在线粒体内膜中，有质子泵功能完全镶嵌在线粒体内膜中，有质子泵功能受体调节（？）完全镶嵌在线粒体内膜中、解偶联剂：寡霉素神经组织和骨骼肌（胞质）神经组织和骨骼肌（线粒体)，生成1.5分子ATP清除超氧阴离子（一种自由基）小肠小肠，中间产物是二酰甘油激素调节限速酶脂肪组织，组织脂肪酶不受激素影响脂肪组织脂肪组织内质网、线粒体外膜外限速酶线粒体外膜内线粒体内膜同工酶线粒体内膜内1.5ATP2.5ATP限速酶β-羟-β-甲戊二酸单酰CoA部分自发脱羧生成丙酮心、肾、脑及骨骼肌的线粒体肾、心和脑的线粒体心、肾、脑及骨骼肌线粒体可使游离甘油得到利用α-磷酸甘油穿梭有类似的反应合成脂肪酸，反向：柠檬酸合酶共价修饰，变构调节，激限速酶生物素起固定CO2和转移羧基的作用脂肪酸合成酶系⑴脂肪酸合成酶系⑵脂肪酸合成酶系⑶脂肪酸合成酶系⑷脂肪酸合成酶系⑹脂肪酸合成酶系⑸脂肪酸合成酶系⑺胞质中进行肝中进行肝、脂肪细胞肝、脂肪细胞肝、脂肪细胞β-羟-β-甲戊二酸单酰CoA激素调节，反馈抑制，共限速酶内质网5C（5C'+5C*2)*2→30C30C→27C+3CO2见于LDL受体途径见于HDL代谢外周组织外周组织酯酶、糖苷酶、酰胺酶等葡萄糖醛酸结合反应，存在于肝脏微粒体硫酸结合反应，3’-磷酸腺苷-5’-磷酰硫酸谷胱甘肽结合反应乙酰基结合反应甘氨酸结合反应甲基结合反应、S-腺苷半胱氨酸激素调节限速酶产物经一系列反应生成胆酸和鹅脱氧胆酸限速酶三种同工酶游离胆红素→结合胆红素（一酯或二酯）反馈抑制PRPP：5-磷酸核糖-1-焦磷酸反馈抑制、竞争性抑制限速酶谷氨酰胺核糖焦磷酸酰胺转移酶；5-PRA：5-磷酸核糖胺GAR：甘氨酰胺核苷酸FGAR：甲酰甘氨酰胺核苷酸FGAM：甲酰甘氨咪核苷酸AIR：5-氨基咪唑核苷酸CAIR：5-氨基咪唑4-羧酸核苷酸SAICAR：5-氨基咪唑4-（N-琥珀基）甲酰胺核苷酸AICAR：5-氨基咪唑4-氨甲酰核苷酸FAICAR：5-甲酰氨基咪唑4-氨甲酰核苷酸反馈抑制、竞争性抑制反馈抑制反馈抑制、竞争性抑制XMP：黄嘌呤核苷酸反馈抑制竞争性抑制R-5-P：汤变构调节反馈抑制限速酶变构调节对胞嘧啶不起作用N代表A、G、U、C等碱基关键酶活化传递识别，与赖氨酸-ε氨基形成“异肽键”又名谷丙转氨酶（GPT）又名谷草转氨酶（GOT）变构调节反应可逆，可与转氨酶联合参与联合脱氨基存在于脑、肌肉存在于肝、肾变构调节关键酶存在于线粒体限速酶GABA（γ-氨基丁酸）是重要的抑制型神经递质L-半胱氨酸氧化成磺酸丙氨酸。

Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Sep.-13-2017Print Date:Sep.-13-20171. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :CalcipotriolCatalog No. :HY-10001CAS No. :112965-21-61.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureNot a hazardous substance or mixture.2.2 GHS Label elements, including precautionary statementsNot a hazardous substance or mixture.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:MC 903; CalcipotrieneFormula:C27H40O3Molecular Weight:412.60CAS No. :112965-21-64. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature: 4°C, protect from light, stored under nitrogenShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 212. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2017 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

Inhibitors, Agonists, Screening LibrariesSafety Data Sheet Revision Date:Jan.-07-2019Print Date:Jan.-07-20191. PRODUCT AND COMPANY IDENTIFICATION1.1 Product identifierProduct name :PSMA-617Catalog No. :HY-117410CAS No. :1702967-37-01.2 Relevant identified uses of the substance or mixture and uses advised againstIdentified uses :Laboratory chemicals, manufacture of substances.1.3 Details of the supplier of the safety data sheetCompany:MedChemExpress USATel:609-228-6898Fax:609-228-5909E-mail:sales@1.4 Emergency telephone numberEmergency Phone #:609-228-68982. HAZARDS IDENTIFICATION2.1 Classification of the substance or mixtureGHS Classification in accordance with 29 CFR 1910 (OSHA HCS)Skin irritation (Category 2), H315Serious eye damage (Category 1), H318Respiratory sensitisation (Category 1), H334Skin sensitisation (Category 1), H317Germ cell mutagenicity (Category 2), H341Reproductive toxicity (Category 2), H361Specific target organ toxicity - single exposure (Category 1), H370Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335Chronic aquatic toxicity (Category 4), H4132.2 GHS Label elements, including precautionary statementsPictogramSignal word DangerHazard statement(s)H315: Causes skin irritation.H317: May cause an allergic skin reactionH318: Causes serious eye damage.H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.H335: May cause respiratory irritation.H341: Suspected of causing genetic defects.H361: Suspected of damaging fertility or the unborn child.H370: Causes damage to organs.H413: May cause long lasting harmful effects to aquatic life.Precautionary statement(s)P201: Obtain special instructions before use.P202: Do not handle until all safety precautions have been read and understood.P260: Do not breathe dust ⁄ fume ⁄ gas ⁄ mist ⁄ vapors ⁄ spray.P264: Wash skin thoroughly after handling.P270: Do not eat, drink or smoke when using this product.P271: Use only outdoors or in a well-ventilated area.P272: Contaminated work clothing should not be allowed out of the workplace.P273: Avoid release to the environment.P280: Wear protective gloves ⁄ eye protection ⁄ face protection.P302 + P352: IF ON SKIN: Wash with plenty of soap and water.P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.P310: Immediately call a POISON CENTER ⁄doctor.P321: Specific treatment (see supplemental first aid instructions on this label).P333 + P313: If skin irritation or rash occurs: Get medical advice ⁄ attention.P362: Take off contaminated clothing and wash before reuse.P403 + P233: Store in a well-ventilated place. Keep container tightly closed.P405: Store locked up.P501: Dispose of contents ⁄ container to an approved waste disposal plant.2.3 Other hazardsNone.3. COMPOSITION/INFORMATION ON INGREDIENTS3.1 SubstancesSynonyms:NoneFormula:C49H71N9O16Molecular Weight:1042.14CAS No. :1702967-37-04. FIRST AID MEASURES4.1 Description of first aid measuresEye contactRemove any contact lenses, locate eye-wash station, and flush eyes immediately with large amounts of water. Separate eyelids with fingers to ensure adequate flushing. Promptly call a physician.Skin contactRinse skin thoroughly with large amounts of water. Remove contaminated clothing and shoes and call a physician.InhalationImmediately relocate self or casualty to fresh air. If breathing is difficult, give cardiopulmonary resuscitation (CPR). Avoid mouth-to-mouth resuscitation.IngestionWash out mouth with water; Do NOT induce vomiting; call a physician.4.2 Most important symptoms and effects, both acute and delayedThe most important known symptoms and effects are described in the labelling (see section 2.2).4.3 Indication of any immediate medical attention and special treatment neededTreat symptomatically.5. FIRE FIGHTING MEASURES5.1 Extinguishing mediaSuitable extinguishing mediaUse water spray, dry chemical, foam, and carbon dioxide fire extinguisher.5.2 Special hazards arising from the substance or mixtureDuring combustion, may emit irritant fumes.5.3 Advice for firefightersWear self-contained breathing apparatus and protective clothing.6. ACCIDENTAL RELEASE MEASURES6.1 Personal precautions, protective equipment and emergency proceduresUse full personal protective equipment. Avoid breathing vapors, mist, dust or gas. Ensure adequate ventilation. Evacuate personnel to safe areas.Refer to protective measures listed in sections 8.6.2 Environmental precautionsTry to prevent further leakage or spillage. Keep the product away from drains or water courses.6.3 Methods and materials for containment and cleaning upAbsorb solutions with finely-powdered liquid-binding material (diatomite, universal binders); Decontaminate surfaces and equipment by scrubbing with alcohol; Dispose of contaminated material according to Section 13.7. HANDLING AND STORAGE7.1 Precautions for safe handlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.7.2 Conditions for safe storage, including any incompatibilitiesKeep container tightly sealed in cool, well-ventilated area. Keep away from direct sunlight and sources of ignition.Recommended storage temperature:Powder-20°C 3 years4°C 2 yearsIn solvent-80°C 6 months-20°C 1 monthShipping at room temperature if less than 2 weeks.7.3 Specific end use(s)No data available.8. EXPOSURE CONTROLS/PERSONAL PROTECTION8.1 Control parametersComponents with workplace control parametersThis product contains no substances with occupational exposure limit values.8.2 Exposure controlsEngineering controlsEnsure adequate ventilation. Provide accessible safety shower and eye wash station.Personal protective equipmentEye protection Safety goggles with side-shields.Hand protection Protective gloves.Skin and body protection Impervious clothing.Respiratory protection Suitable respirator.Environmental exposure controls Keep the product away from drains, water courses or the soil. Cleanspillages in a safe way as soon as possible.9. PHYSICAL AND CHEMICAL PROPERTIES9.1 Information on basic physical and chemical propertiesAppearance White to off-white (Solid)Odor No data availableOdor threshold No data availablepH No data availableMelting/freezing point No data availableBoiling point/range No data availableFlash point No data availableEvaporation rate No data availableFlammability (solid, gas)No data availableUpper/lower flammability or explosive limits No data availableVapor pressure No data availableVapor density No data availableRelative density No data availableWater Solubility No data availablePartition coefficient No data availableAuto-ignition temperature No data availableDecomposition temperature No data availableViscosity No data availableExplosive properties No data availableOxidizing properties No data available9.2 Other safety informationNo data available.10. STABILITY AND REACTIVITY10.1 ReactivityNo data available.10.2 Chemical stabilityStable under recommended storage conditions.10.3 Possibility of hazardous reactionsNo data available.10.4 Conditions to avoidNo data available.10.5 Incompatible materialsStrong acids/alkalis, strong oxidising/reducing agents.10.6 Hazardous decomposition productsUnder fire conditions, may decompose and emit toxic fumes.Other decomposition products - no data available.11.TOXICOLOGICAL INFORMATION11.1 Information on toxicological effectsAcute toxicityClassified based on available data. For more details, see section 2Skin corrosion/irritationClassified based on available data. For more details, see section 2Serious eye damage/irritationClassified based on available data. For more details, see section 2Respiratory or skin sensitizationClassified based on available data. For more details, see section 2Germ cell mutagenicityClassified based on available data. For more details, see section 2CarcinogenicityIARC: No component of this product present at a level equal to or greater than 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.ACGIH: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by ACGIH.NTP: No component of this product present at a level equal to or greater than 0.1% is identified as a anticipated or confirmed carcinogen by NTP.OSHA: No component of this product present at a level equal to or greater than 0.1% is identified as a potential or confirmed carcinogen by OSHA.Reproductive toxicityClassified based on available data. For more details, see section 2Specific target organ toxicity - single exposureClassified based on available data. For more details, see section 2Specific target organ toxicity - repeated exposureClassified based on available data. For more details, see section 2Aspiration hazardClassified based on available data. For more details, see section 2Additional informationRTECS No.: DA8340700Alopecia., Liver injury may occur., Kidney injury may occur., Nausea, Headache, Vomiting, bone marrow depression.This information is based on our current knowledge. However the chemical, physical, and toxicological properties have not been completely investigated.12. ECOLOGICAL INFORMATION12.1 ToxicityNo data available.12.2 Persistence and degradabilityNo data available.12.3 Bioaccumlative potentialNo data available.12.4 Mobility in soilNo data available.12.5 Results of PBT and vPvB assessmentPBT/vPvB assessment unavailable as chemical safety assessment not required or not conducted.12.6 Other adverse effectsNo data available.13. DISPOSAL CONSIDERATIONS13.1 Waste treatment methodsProductDispose substance in accordance with prevailing country, federal, state and local regulations.Contaminated packagingConduct recycling or disposal in accordance with prevailing country, federal, state and local regulations.14. TRANSPORT INFORMATIONDOT (US)This substance is considered to be non-hazardous for transport.IMDGThis substance is considered to be non-hazardous for transport.IATAThis substance is considered to be non-hazardous for transport.15. REGULATORY INFORMATIONSARA 302 Components:No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.SARA 313 Components:This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.SARA 311/312 Hazards:No SARA Hazards.Massachusetts Right To Know Components:No components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know Components:No components are subject to the Pennsylvania Right to Know Act.New Jersey Right To Know Components:No components are subject to the New Jersey Right to Know Act.California Prop. 65 Components:This product does not contain any chemicals known to State of California to cause cancer, birth defects, or anyother reproductive harm.16. OTHER INFORMATIONCopyright 2019 MedChemExpress. The above information is correct to the best of our present knowledge but does not purport to be all inclusive and should be used only as a guide. The product is for research use only and for experienced personnel. It must only be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. The burden of safe use of this material rests entirely with the user. MedChemExpress disclaims all liability for any damage resulting from handling or from contact with this product.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: tech@Address: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA。

尿素-SDS-PAGE显示干酪成熟过程中酪蛋白降解生成的小分子多肽郑小平;陈有容;郭本恒【期刊名称】《乳业科学与技术》【年(卷),期】2002(025)002【摘要】本文采用尿素-SDS-PAGE对多肽标准品Marker I(2512-16949)的分子量进行了测定,并对干酪成熟过程中酪蛋白降解生成的小分子多肽进行了分析.结果表明,采用16%T,6%C的分离胶,6%T,3%C的浓缩胶,6mol/L的尿素分析系统能清楚地显示分子量为2512-16949的小分子多肽,多肽标准品的直线回归系数R2=0.9948,样品在固定、染色和脱色过程中不易扩散丢失,不需特殊染色方法,该法是显示小分子多肽物质的简单、快速、有效的方法.对成熟30天的霉菌干酪样品进行分析结果表明,样品中的酪蛋白降解后生成了大量的小分子多肽物质(分子量＜10000Da).【总页数】3页(P7-9)【作者】郑小平;陈有容;郭本恒【作者单位】上海水产大学食品学院,上海,200090;上海光明乳业股份有限公司技术中心,上海,200072;上海光明乳业股份有限公司技术中心,上海,200072【正文语种】中文【中图分类】TS2【相关文献】1.干酪乳杆菌LC2W对切达干酪蛋白质降解的影响 [J], 贾宏信;龚广予2.尿素-SDS-PAGE测定小分子多肽相对分子质量方法的建立 [J], 王丽荣;程福亮;陈雷;谷巍3.不同发酵剂菌种对Mozzarella干酪成熟过程中蛋白降解及风味形成的影响 [J], 白建;赵建英;薛建娥;刘奥强;王亚捷4.提高成熟温度对牦牛乳硬质干酪蛋白质降解的影响 [J], 宋雪梅;梁琪;张卫兵;张炎;包振荣5.应用SDS-PAGE显示小分子多肽技术的探讨 [J], 石继红;赵永同;张英起;颜真;韩苇;王俊楼因版权原因，仅展示原文概要，查看原文内容请购买。