专业英语短语:Extracted from “Hydrogels for
protein delivery in tissue engineering”Caused by;
Present enormous challenges in;
Lead to;
The combination of…and;
Provides an overview of;
Be proposed to;
Have remarkable relevance关联;
An outlook on future directions;
Be provided;
An introduction to;
Protein release strategies from;
Controlled drug delivery;
Has seen rapid advances;
In all ?elds of pharmaceutical and biomedical sciences;
with the advent(到来) of protein therapeutics;
Became more urgent;
The need for;
Where supply of bimolecular cues;
Mimic the environment of natural tissues;Promote the communication;
Aims at;
Have emerged as particularly promising materials for;
Can act both as…and/or;
In a controlled fashion;
This mini-review brie?y describes;
After highlighting the rationale(基本原理) for;
Involved in healing processes;
Strategies for encapsulation;
Are also discussed;
Hydrogel-based;
With potential clinical impact;
Are outlined(概述);
Are highly influenced by;
Interactions with The surrounding microenvironment
Create an effective communication between … and;
Leads to;
Identified as key components of;
Play a pivotal role in关键;
Are difficult to
It is currently widely accepted that
The self-healing capacity of
Can be augmented by
By the integration of
Accelerate
Promote the re-growth
, owing to their short half-lives
Has a half-life of only 3 min/has a half life of Less than 2 min
…, that modulate;
Unlike other proteins (i.e. hormones),…;
To mention, …
Similarly,
Are needed to do;
, isolated from platelets,
The exogenous administration of growth factors;
Faces important limitations
Associated to
Their poor transdermal adsorption
Are frequently used to
To direct the protein speci?cally to the wound site;
In a controlled and effective manner; Spatiotemporal control over the delivery of Not only…, but also
But also prevents
Unwanted and potentially harmful side-effects at other locations than the target;
Have been investigated to;
Occurs through
Via
Are embedded in
Is based on a combination of mechanisms Rely on
Are secreted by
That are encapsulated in
In the following section
Will be discussed
Can be loaded into
Can be physically entrapped in
Be adsorbed to
Combination of multiple delivery systems Depending on the release mechanism Different release pro?les can be obtained Table 2 overviews
In order to obtain
Physical encapsulation of growth factors
Is a frequently applied technique for
In recent years,
Attention is shifted to in situ gelling systems At the site of injection
Typically, the mechanisms that govern the drug release from these hydrogels are controlled by diffusion, swelling, erosion, external stimuli or combinations thereof [43] Depends on both…a nd
Generally speaking,
The majority of the gel matrices
Following Higuchi's kinetics,
Implying that the release is proportional to the square root of time
This release pro?le
Was demonstrated particularly bene?cial for Demonstrated that
Was released down a concentration gradient Proved effective not only…, but also
Is governed by
, resulting in
As a consequence因此,
Polymer disentanglement (解缠) and dissolution
Increased in number
In these systems
The mobility of the drug迁移率
Is limited
Is then governed by
The degradation rate of the polymer, porosity increase, and drug diffusion
Mainly in the surface of
The possibility to tailor the release kinetics of Can be achieved through
By changing
In this particular instance例子,
Is extremely advantageous because
Offer the opportunity to
Can be tailored
To some extent
By changing
Extensive work on the development of hybrid networks,in which natural polymers are synthetically modi?ed or combined with synthetic polymers,
Has been proposed to
With respect to关于、至于
In terms of
Biodegradability as well as biocompatibility and cytocompatibility
Generally, the bigger is the device, the longer the diffusion distances become and the longer the release consequently lasts
Utilized in tissue engineering
Adjust surface area
Modulate release pro?les
Deviation from the described release behaviors
For instance
Hydro gels swell or shrink in response to a certain trigger thereby从而modulating the release of encapsulated drugs/proteins Among the various synthetic polymers,
Play a prominent role.
Investigated the feasibility of
For this purpose,
Were synthesized
Formed by
Transected with转染
In control culture conditions
Because they offer several bene?ts, including…
For instance,
Are dictated by口述
Alters network degradation rates改变
Apply to
, like those based on
Were processable可加工的
It was shown that upon subcutaneous injection (rat model) the hydrogels were stable for one month.
Was loaded into
Used as a slow releasing drug reservoir容器Aimed for wound healing purposes
Were observed
With no initial burst and a good correlation 关联with in vivo data,
, that con?rmed
A weight gain in hypophysectomized垂体切除术rats equivalent to conventional daily injections of 5 mg pGH for 14 consecutive连续的days
Released over a 12-day period and similarly to pGH,
, showed similar ef?cacy功效in rats as compared to daily i.v. injections
Proteins are released from this network by Fickian diffusion
Can be tailored by tuning调试
Showed a good biocompatibility in
Their potential for
Has been demonstrated
Was introduced by Zhang et al.
Consist of
Are able to spontaneously self-assemble(vi)into
That are needed for the peptide assembly组装are sequestered (分开) from
The described family of peptides
The observed slow and controlled release of has been ascribed to diffusion归因于Amphiphilic nature两亲性of the self-assembling polypeptide
Leads to interactions with
, resulting in
Showed degradation mediated (…调制的) release of model proteins
That potentially can be used to physically encapsulate and release growth factors with zero order release kinetics
Inclusion complexes包含配合物Have also been investigated for
, reversibly crosslinked by可逆地
The polymer forming the hydrogel is based on
Functionalized with…功能化
The addition of …
Be partly broken,
Comprising包括、包含
Were studied for
Is triggered by
Capable of degrading
They in?uence cell behavior
Were developed with the aim to
Mimic模仿the natural processes
Involved in tissue repair
Use PEG as the main building block
It has been shown to act as
In the presence of
The bene?ts of this approach
Showed a 50% increase in perfusion to灌注到the feet as compared to untreated mice
, indicating that
Has itself a bene?cial healing or supportive effect
, acting synergistically协同地as a directive 指导性的scaffold and a growth factor delivery vehicle
Display multiple多重的advantages over With respect to
Is available on对…有效
In regenerative medicine
The main classes(类别)of
Are therefore因此very suitable fo r
Aimed for
Representatives of
Are briefly discussed below
With respect to
Linear poly saccharide
Composed of
Linked
In different sequences序列or blocks块、区位
So-called
Arrangement
Are therefore particularly appealing for吸引力
Prolonged延长的
Some limitations in
Tailoring the mechanical properties Remain
To overcome
Studie its potential to
Induce angiogenesis血管生成in vivo
Cross-linkable成型的
Affinity-binding密切关系
It was shown that
By partial cross-linking in presence of CaCl2 , as described for
Combine the advantageous properties优点of
, derived from
Of which the mechanical properties were notably显著地improved by
Proved effective in
In another study,
Were covalently modified with
Were lyophilized to form
Micro porous scaffolds多微孔的
Induce neo vascularization新的
It was observed that
Were viable可行的
During the studied time frame框架
Migrate out of迁移
Was effective in
With some degree of
Presents many options for
…relevant for有关的
Is derivatized with改性
Was driven by
Was dependent on
It was found that
Released by diffusion/swelling
Fig. 3. Analysis of angiogenesis…
More recently,
Susceptible to敏感的
Bifunctional双功能的
It was demonstrated that Showed diffusional release扩散
Multiple growth factors
Mixed at different ratios and subsequently随后,
Was favored有利的by reducing
Reduced rigidity硬度
Rapid hydrogel disintegration 崩解、分解Furthermore,
Be processed into加工、处理
Naturally occurring天然存在
Molecular weights up to 107 Da
Because of its biocompatible,
Is an extensively studied
For the development of delivery systems Displays poor差的mechanical properties
To be suitable for protein delivery, Introduce functionalities功能、功能团
Be correlated有关with the mass erosion With different crosslink densities
Mature bone
Additionally, the co-delivery of an angiogenic molecule (VEGF) in conjunction with协同、连同an osteoinductive molecule (BMP-2) increased the extent of范围formed mineralized tissue
Were studied for
The delivery of multiple growth factors
In both presence or absence of heparin
, according to
Were conducted by指挥
It was found that release followed遵循first order kinetics,
, with gelatin slightly increasing the growth factor release rate,
The extent of revascularization
Will be affected by
Generally speaking 一般而言
Cationic阳离子
The polymer
Is positively charged at low pH's Make…suitable for
Was realized by
The azido叠氮基groups are converted into nitrenes氮烯
80% of initially loaded VEGF was retained in the network
Reviews on
Published concerning关于their drug/protein delivery aspects
Are naturally occurring发生
Been extensively exploited as main component in matrices for
Can be detrimental for有害于
Diffusion coefficients
With a variety of各种
Leading to slightly different polymer properties
Can be tailored precisely
Are gradually resorbed (吸收) in vivo by Was later covalently bound to
By enzymatic cleavage
Reported on
An elegant 讲究的approach on the multimodal 多模式的、多峰的release of With distinct独特的kinetics
Via3 mechanisms: entrapment, conjugation 结合through a homobifunctional amine reactive PEG linker, and physical adsorption on the fibrin matrix
Was both conjugated共轭、结合through Bound to the matrix via束缚于
Was highly correlated to
As compared to
To manipulate操纵、控制drug loading and control release kinetics
The easiest method to modulate
Retard drug release延迟
Possesses a specific binding domain for Deals only with
One approach to…in
Is to covalently link
Bi-domain
As compared to fibrin hydrogels
Were reacted with
Some challenges still remain such as
To predict the release rate of proteins from Be coupled to连接,组对
Was tailored by altering Can vary from noncovalent bonds to
Huge challenges still exist with
Bound to polymer matrices via functional groups like hydroxy, amine, carboxyl groups that
If not naturally present in the structure of the polymer, have to be introduced by functionalization reactions,
However, stability and maintenance维护of biological activity of the protein may represent an issue
susceptible to(对…敏感)
Have considerable重要的、值得考虑的potential as
Is a common approach to?
That facilitated促进
In a synergistic协同的manner
Strongly depended on
Complex interplay相互作用
For independent delivery of
To achieve a diversity多样性、差异性of release
Profiles,
Dispersed within分散
Their synergistic interplay
Is nowadays a well-established concept得到确认的
Resulted from
On the other hand,
allow to sustain the release
including traditional diffusion/swelling/degradation mediated, However, some challenges still exist
This project was financially supported by…Extracted from “The use of injectable sonication-induced silk hydrogel for VEGF 165 and BMP-2 delivery for elevation of the maxillary sinus floor”
The use of
Sanitation-induced卫生
, with a need to
Are key regulators of angiogenesis and
osteogenesis
The present study aimed at evaluating
As
A vehicle to encapsulate dual factors for
For in vivo studies for each time point (4 and 12 weeks),
Bilaterally双边地
Four treatment groups: silk gel (group Silk gel), silk gel/VEGF165 (group VEGF), silk gel/BMP-2 (group BMP-2), silk gel/VEGF165/BMP-2 (group V+ B) (n=6 per group).
Promoted more tissue infiltration into
Was significantly larger than those
As a consequence,
Has been a focus
With advantages of
Low inflammatory response because of Suggest its potential use as
The combination of VEGF and BMP-2 offers synergy toward bone regeneration
Play a central role
With an average weight of 2.5 kg
Were obtained from
The experimental protocol协议was approved by the Animal Care and Experiment Committee of Ninth People’s Hospital
In 0.02 M sodium carbonate aqueous solution
Rinsed thoroughly with deionized water After overnight drying,
Extracted from “Tunable dual growth factor delivery from polyelectrolyte multilayer films”
Tunable dual growth factor delivery
Deliver a combination of certain growth factors to the integration site整合位点
A promising strategy to/for…There is a need to
To maximize efficacy效力
Are attractive for吸引人的
Over a sustained period
Eluted from洗脱
, as quantified with以…定量relevant in vitro assays
Initiated a dose
Dependent differentiation cascade级联、串联、小瀑布in while rhVEGF165 upregulated上调HUVEC proliferation, and accelerated closure of a scratch in HUVEC cell cultures in a dose dependent manner剂量依赖性
The mineral density of ectopic bone formed de novo by rhBMP-2/rhVEGF165 PEM films Was approximately33% higher than when only rhBMP-2 was introduced
In the risk of osteoporotic骨质疏松性fracture
Bone formed throughout the scaffold
Which suggests more complete remodeling? Due to an increased增加的local vascular network
This study demonstrates a promising approach to doing
Delivering precise doses严格的剂量of multiple growth factors for
A variety of implant applications
Is desired渴望的、想得到的
Control over控制、支配
Approximately 10% of total
Within 10 years
Almost entirely because of
The failure of exaction苛求
In cases of万一
It is necessary to address the bone as从事、忙于
Integrating整合
The implant with the bone tissue
Have been shown to
Be some of the most potent权势的、有力的…
Known amongst
Capable of directly inducing…
Both ectopic异位的and orthotropic正位的sites
Is an approved被认可的product for use on? More complete bone remodeling再造
Over shorter time periods
Critical for
Intramembranous膜内的and endochondral软骨内的bone formation
Is required for
Is a critical component of关键元素、关键部件
Is greatly enhanced by
The introduction of rhVEGF has been shown to enhance bone formation
Increased blood ?ow
Localized局部的introduction of such growth factors
There is a therapeutic有疗效的advantage to…
The delivery of growth factors in vivo presents many complex challenges
In case万一
Control over the amount of
At high temperature
By exposure
To unfavorable solvents溶剂、解决方法or through the development of a low pH environment
At a minimal dose level
Over prolonged time periods of several weeks
Prior to the introduction of rhBMP-2
With a corresponding dose dependent effect on…
Method is unique in its ability to
Preserve fragile protein activity.
Due to the need for sequential and controlled delivery of…
Initiate the different cellular cascade
Can yield idealized release behavior
Was obtained from
Were purchased from
Dipping solutions containing含有PEA and chondroitin sulfate were prepared at 2 mg/mol in 100 mM sodium acetate buffer
RhBMP-2 and rhVEGF165 dipping solutions were 40 mg/ml in 100 mM sodium acetate buffer
Were replaced
Were replenished重新充满every 24 h by adding
Were fabricated on this scaffold with
With the following protocol协议
Swapped for交换
Concurrently同时地、一致地
The ?nal product was stored at4 C until released or implanted.
Were released at 37 C into 1mL of 1x PBS in 1.7 ml centrifuge tubes
At a series of predetermined预定的time points,
Containing fresh 1ml PBS
Samples were analyzed using ELISA development kits according to manufacturer instructions说明书
Consecutive连贯的time points
To test the efficacy效力of
A number of in vitro tests were performed执行to
BMP-2 initiates the differentiation of preosteoblast cell line
Each condition was repeated in triplicate三倍份
Supplemented with增补、补充
Cells were cultured under different experimental conditions
Was determined on day 5 after…by…
Or one freeze-thaw cycle
Were transferred to转移
Centrifuged at 15,000g for 3 min at 4C
The ALP activity measurements were normalized to标准化total protein determined by BCA assay
After 14 days of exposure to different formulations of the release medium,
Were assayed for calcium deposition using Washed in distilled water 4 times for 5 min each
Were disrupted破坏、分裂by the use a pipette tip吸管端
Vortexes for 30 s 旋涡
Heated at 85C for 10 min
Were read on a 96-well plate with black sides and a clear bottom at 405 nm
The normalized rhVEGF165dose per milligram of scaffold was calculated, Labeled with…for another 2 h
The absorbance was measured at 450 nm with a 595 nm reference wavelength
All animal work was performed in accordance with protocols approved by the Committee on Animal Care at Massachusetts Institute of Technology.
(Corresponding to a 6 mg total scaffold load),
动物实验步骤:The right hind limb of each animal was shaved, cleaned with alcohol and povidone iodine solutions, and sterile drapes were placed around the surgical area
Post-operatively,
Four rats from each group were sacrificed and the implants retrieved for analysis as described below
Excised切离的samples were immediately placed in
Solutions of 70% ethanol
Prior to decalcification脱钙
in a solution of 15% EDTA and 10% sodium citrate buffer, pH 7.2 at 4C under continuous stirring
Were then serially sectioned切开, routinely processed, and embedded in paraffin. Microscope sections (4um) were stained with…
Fabricating a dual growth factor releasing layer-by-layer system
Have a molecular weigh t of about 30 kDa and 38.2 kDa respectively.
Under conditions of acidic and physiological pH,
Are expected to be
For the layer-by-layer film assembly, we used Which has been extensively studied in
For various delivery applications
Under neutral to acidic pH conditions of
Are protonated, yielding the positive charge? Necessary for
We anticipated that预料
Suitable for
Would initiate
The choice of scaffold was governed by the following factors: (i)…
Compared with a flat film
The precise growth factor dose required would depend on the specific orthopedic application
A dose response behavior
This system could be tuned for specific applications
was normalized to标准化
We tuned our system to demonstrate
A control over total growth factor loading Occurs with a pH shift from…to…Approximately one-third of the rhBMP-2 and two-thirds of the rhVEGF165was released after three days
It takes a longer time to elute completely from
Is comparable可比较的
That is not always readily attained with multilayer formulations剂型
Leach out of…into the dipping solution Electrostatic interactions between the growth factor and surrounding polymer chains链
Prevent it from diffusing out
4.50+-0.14 ng ( R2= 0.93) and 3.72+-0.080 ng (R2= 0.96)
Ranged from 250 to 600 ng/mg
, as a function of根据number of layers
A broad range of protein incorporation in Film would undergo bulk erosion
The dominance优势of surface erosion
Is consistent一致的across the different groups
After which there is no detectable可检测的
release
It is interesting to note that
The amount of rhVEGF165 released
Drops to 15+_ 1.42%
It is likely可能的that
Interdiffusion互扩散occurs
Have been reported for similar systems
In vitro rhBMP-2 activity assay
RhBMP-2 dose dependent behavior of…Exposed …to
Is dose dependent to the amount of rhBMP-2 its visualization形象化and quantification 量化
Mature bone phenotype表现型
Observed to be rhBMP-2dose dependent (Fig. 3D, E, F) (p < 0.05) at constant dose was more diffuse发散
Complimentary to these findings,补充的Substituting for取代…
Reaching confluency整合
Which was statistically significant(Fig. 4A, B) (p<0.05)
Which is consistent with observations elsewhere [50]
Was statistically insignificant
Migration of迁移
confluent monolayer整合的
As a function of根据
Maturation of ectopic bone Microcomputer tomography (microCT) …time points
Showed large bone deposits created in response to rhBMP-2 LbL films Progressively逐步地increased in thickness In contrast,
Was restricted to the periphery外围、周围of the scaffold
Over the initial 4 week time period,
A greater amount of bone was present
Deep within scaffold
Interior…内部的
Was found to be3 fold and 4.5 fold greater “…倍大”than the bone
This is important, as it demonstrates that as visualized by通过…看到
Is visible
Is progressively replaced with
De novo recapitulation概括
concurrent并发的、一致的Aforementioned上述的biological processes Is a potent tool for
The ability to regulate
At distinct明显的stages
been well documented记录
monogram scale纳克级physiological amounts of
Over different timeframes
…using sustained release obtained with hydrolytic degradation
Compared to…
…such that…
Flexible灵活的,
A wide variety of
Step toward developing…
From implant coatings to tissue engineering Conflict of interest: The authors confirm that there are no known conflicts of interest associated with this publication. Acknowledgments: This work was funded by 由…资助
100句经典英文短句 1. I see. 我明白了。 2. I quit! 我不干了! 3. Let go! 放手! 4. Me too. 我也是。 5. My god! 天哪! 6. No way! 不行! 7. Come on. 来吧(赶快) 8. Hold on. 等一等。 9. I agree。我同意。 10. Not bad. 还不错。 11. Not yet. 还没。 12. See you. 再见。 13. Shut up! 闭嘴! 14. So long. 再见。 15. Why not? 好呀! (为什么不呢?) 16. Allow me. 让我来。 17. Be quiet! 安静点! 18. Cheer up! 振作起来! 19. Good job! 做得好! 20. Have fun! 玩得开心! 21. How much? 多少钱?
22. I'm full. 我饱了。 23. I'm home. 我回来了。 24. I'm lost. 我迷路了。 25. My treat. 我请客。 26. So do I. 我也一样。 27. This way。这边请。 28. After you. 您先。 29. Bless you! 祝福你! 30. Follow me. 跟我来。 31. Forget it! 休想! (算了!) 32. Good luck! 祝好运! 3 3. I decline! 我拒绝! 34. I promise. 我保证。 35. Of course! 当然了! 36. Slow down! 慢点! 37. Take care! 保重! 38. They hurt. (伤口)疼。 39. Try again. 再试试。 40. Watch out! 当心。 41. What's up? 有什么事吗? 42. Be careful! 注意! 43. Bottoms up! 干杯(见底)!
经典英语句子 1、Love is not geting but giving. 爱是付出,不是占有。 2、If I cried a tear of painful sorrow,If I lost all hope for a new tomorrow,Would you dry my tear and ease my pain,Would you make me smile once again? 如果我因深深的悲哀而痛哭,如果我已对明天失去了所有的希望,你是否会为我擦去泪水,抚平伤痛,你是否会让我欢颜依旧? 3、If you love the life you live,you will live a life of love. 如果你爱你的生活,你的生活就会充满爱。 4、how do i say i love you? how do i tell you i care? how do i tell you ive missed you, and let you know im here? 我如何说我爱你?我如何告诉你我在乎你?我如何告诉你我一直都在想你?如何让你知道我就在这里? 5、Love cures people both the ones who give it and the ones who receive it. 爱能医人奉献者和接受者皆然。 6、Her gesture, motion, and her smiles,Her wit, her voice my heart beguiles,Beguiles my heart, I know not why,And yet, 1 / 6
英语励志名言大全
英语励志名言大全 1、believe in yourself. 相信自己! 2、consider things from every angle. 思考问题要全面。 3、don't give up and don't give in. 不要放弃,不要言败! 4、want it more that anything. 必须之物最重要。 5、xcellerate your efforts. 加倍努力! 6、zero in your target,and go for it. 从零开始,勇往直前! 7、give more than you planned to. 多多给予,不必计较。 8、hang on to your dreams.
追逐梦想。 9、ignore those who try to discourage you . 阴险与打击勿放心上。 10、take control of your own desting. 命运掌握在自己手上。 11、live well, love lots, and laugh often. 善待生活,热爱一切,经常开怀大笑。 12、open your eyes and see things as they really are. 睁大眼睛,看清事实真相。(励志名言https://www.doczj.com/doc/978043824.html,) 13、quitters never win and winners never quit. 退缩者永无胜利,胜利者永不退缩。 14、you're uinique, nothing can replace you. 你举世无双,无人可以替代。 15、understand yourself in order to better understanding others. 知己方能解人。 16、keep trying no matter how hard it seems. it will get easier.
1. 随着经济的繁荣with the booming of the economy 2. 随着人民生活水平的显著提高with the remarkable improvement of people's living standard 3. 先进的科学技术advanced science and technology 4. 为我们日常生活增添了情趣add much spice / flavor to our daily life 5. 人们普遍认为It is commonly believ ed that… 6. 我同意前者(后者)观点I give my vote to the former / latter opinion. 7. 引起了广泛的公众关注Sth. has aroused wide public concern. / Sth has drawn great public atte ntion. 8. 不可否认It is undeniable that… 9. 热烈的讨论/ 争论a heated discussion / debate 10. 有争议性的问题a controversial issue 11. 就我而言/ 就个人而言As far as I am concerned, / Personally, 12. 有充分的理由支持be supported by sound reasons 13. 双方的论点argument on both sides 14. 发挥日益重要作用play an increasingly important role in… 15. 对…必不可少be indispensable to … 16. 正如谚语所说As the proverb goes: 17. 对…产生有利/不利的影响exert positive / negative effects on… 18. 利远远大于弊The advantages far outweigh the disadvantages. 19. 导致,引起lead to / give rise to / contribute to / result in 20. 复杂的社会现象a complicated social phenomenon 21. 责任感/ 成就感sense of responsibility / achievement 22. 竞争与合作精神sense of competition and cooperation 23. 开阔眼界widen one's horizon / broaden one's vision 24. 学习知识和技能acquire knowledge and skills 25. 经济/心理负担financial burden / psychological burden 26. 考虑到诸多因素take many factors into consideration 27. 从另一个角度from another perspective 28. 做出共同努力make joint efforts 29. 对…有益be beneficial to / be conducive to… 30. 为社会做贡献make contributions to the society 31. 打下坚实的基础lay a solid foundation for… 32. 综合素质comprehensive quality 33. 致力于/ 投身于be committed / devoted to… 34. 应当承认Admittedly, 35. 不可推卸的义务unshakable duty 36. 满足需求satisfy / meet the needs of... 37. 可靠的信息源a reliable source of information 38. 宝贵的自然资源valuable natural resources 39. 因特网the Internet (一定要由冠词,字母I 大写) 40. 方便快捷convenient and efficient 41. 在人类生活的方方面面in all aspects of human life 42. 环保的材料environmentally friendly materials 43. 社会进步的体现a symbol of society progress
短语句子积累 Granted that (=because of the fact that) it is a simple test to perform, it should be easy to get results quickly. instill a can-do attitude in/into their children instill confidence/discipline/fear into sb.(逐步使某人树立信心/守纪律/产生恐惧) high efficiency and good teamwork feel overwhelmed with Sending your child off to elementary school for the first time can be daunting(令人怯步的). be acquainted with 对……熟悉 back all the way 一直支持 It hasn’t been easy, but it’s rewarding(值得做的)——for me and my family. Seize today, put no trust in tomorrow. We must apply what we have learned to our daily work because in no case should theory be separated from practice. be capable of distracted张皇失措的,心烦神乱的` I look on it as an opportunity to acquire fresh skills. You become a winner the instant you believe in you can win. It’s helpful to put children in a situation where they manage everything all by themselves.
经典英语句子大全 导读:本文是关于句子大全的文章,如果觉得很不错,欢迎点评和分享! 1、想你了,想躺在你怀里,安心的趴在你身上晒太阳,想你狠狠的抱着我搂着我疼着我。 Think of you, want to lie in your arms, comfortably lying on your body to bask in the sun, think of you ruthlessly hug me, hug me and hurt me. 2、现在的女生不能爱,老是表面心里坏,他说爱你一辈子,其实爱你一整子。 Nowadays girls can't love, they always have a bad heart on the surface. He said that he loves you all his life, but in fact he loves you all his life. 3、如果不想浪费光阴的话,要么静下心来读点书,要么去赚点钱。这两点对你将来都有用。 If you don't want to waste your time, either settle down to read or make some money. These two points will help you in the future. 4、在什么都不确定的年代,我们总是爱得太早、放弃得太快,轻易付出。 In an age of uncertainty, we always love too early, give up
too quickly, and pay easily. 5、男人思念一个人,是在酒后半醉的时候;女人思念一个人,是在深夜失眠的时候。 Men miss a person when they are half drunk after drinking; women miss a person when they are insomnia at night. 6、爱是一念之差,最幸福的不过是,你曾温柔呼唤,而我恰好有过应答。 Love is a difference of thought. The happiest thing is that you called softly and I happened to answer. 7、当幻想和现实面对时,总是很痛苦的。要么你被痛苦击倒,要么你把痛苦踩在脚下。 When fantasy and reality are faced, it is always painful. Either you are knocked down by pain, or you trample on it. 8、“后来”这个词,概括了所有我们不想要改变,却又面目全非了的事。 The word "later" sums up all the things that we don't want to change but are totally different from each other. 9、我可以一直傻下去,但绝不会傻到连自己都陌生,所以,别己他人的善良,欺骗自己的智商。 I can be foolish all the time, but I will never be so foolish as to be unfamiliar with myself, so don't deceive my IQ by being kind to others.
高中必背英语短语(经典版)
1. be afraid of 担心恐怕 2. agree to do sth. 同意做某事 3. not…at all一点也不 4. one after another 一个接一个 5. at last 最后 6. at once 立即马上 7. at the same time 同时 8. at work 在上班 9. be away from 远离 10. go away 走开 11. make the bed 整理被物 12. do one’s best尽某人最大的努力 13. be busy with 忙于干某事 14. be busy doing sth忙于做某事 15. by bus /car / plane 乘公汽打的乘飞机 16. catch up with 迎头赶上 17. catch cold 感冒 18. day after day 一天又一天 19. do some cleaning 使干净 20. eat up / use up 吃光用光 21. in the end 最后最终 22. fall ill 生病 23. on foot 步行 24. make friends with sb. 与某人交朋友 25. in front of 在。。。。前方 26. get back /in /off /on 返回、得到 27. get on with 与某人相处 28. give up 放弃 29. go on doing sth. 继续干某事 30. go shopping 购物 31. be good at 在某方面擅长 32. hand in / out 交上承上 33. have a good time 旅途愉快 34. have breakfast / supper 吃早餐/午餐
很短,但是会给你打很高分的英语口语集锦 转载自:赵佳兴转载于:今天08:18 | 分类:个人日记阅读:(1) 评论:(0) God works. 上帝的安排。 Not so bad. 不错。 No way! 不可能! Don't flatter me. 过奖了。 Hope so. 希望如此。 Go down to business. 言归正传。 I'm not going. 我不去了。 Does it serve your purpose?对你有用吗? I don't care. 我不在乎。 None of my business. 不关我事。 It doesn't work. 不管用。 Your are welcome. 你太客气了。 It is a long story. 一言难尽。 Between us. 你知,我知。 Sure thin! 當然! Talk truly. 有话直说。 I'm going to go. 我這就去。 Never mind. 不要緊。
Why are you so sure?怎么这样肯定? Is that so?是这样吗? Come on, be reasonable. 嗨,你怎么不讲道理。When are you leaving?你什么时候走? You don't say so. 未必吧,不至于这样吧。Don't get me wrong. 别误会我。 You bet! 一定,当然! It's up to you. 由你决定。 The line is engaged. 占线。 My hands are full right now. 我现在很忙。 Can you dig it?你搞明白了吗? I'm afraid I can't. 我恐怕不能。 How big of you! 你真棒! Poor thing! 真可怜! How about eating out?外面吃饭怎样? Don't over do it. 别太过分了。 You want a bet?你想打赌吗? What if I go for you?我替你去怎么样? Who wants?谁稀罕? Follow my nose. 凭直觉做某事。 Cheap skate! 小气鬼! Come seat here. 来这边坐。
经典的英文句子: 1.Be yourself and stay unique.Your imperfections make you beautiful,lovable, and valuable.——做最特别的自己,正因为你的不完美,你才如此美丽、可爱、珍贵…… 2.Don't aim for success if you want it; just do what you love and believe in, and it will come naturally. ——如果你想要成功,不要去追求成功;尽管做你自己热爱的事情并且相信它,成功自然到来。 3.Sometimes, the simplest advice that you give to others is the hardest thing for you to follow.?有时候,你给别人最简单的建议,却是自己最难做到的 4.If you love someone, put his name in a circle not a heart, because a heart can be broken, a circle goes on forever. ?如果你爱上一个人,把他的名字放进一个圆,而不是心。因为心会破碎,而圆永远不会 5.If you want something you've never had, then you've got to do something you've never Done.?如果你想要你从未拥有过的东西,那么你必须去做你从未做过的事 6.If the relationship doesn't make you a better person, then you are with the wrong one. ------ 如果一段感情,没有把你变成更好的人,那么很遗憾你跟错了人。 7.I wish I could find someone who would feel my pain even though I'm saying OK with a smile.——我希望找到这样一个人,即使我微笑着说“我还好”的时候,他也能察觉得到我的痛苦。 8.Memories, beautiful very hurt, memories, memories of the past but can not go back.?回忆,很美,却很伤;回忆,只是回不到过去的记忆。 9.Never give up your right to be wrong, because then you will lose the ability to learn new things and move forward with your life. ?永远不要放弃犯错的权利,因为如果那样,你就失去了学习新事物、推进生活的能力? 10.If we can only encounter each other rather than stay with each other, then I wish we had never encountered. ?如果只是遇见,不能停留,不如不遇见? 11.Sometimes you will never know the true value of a moment until it becomes a memory. 有时候,直到一些珍贵的时刻变成了回忆,你才会真正意识到它的价值所在? 12.The God only arranges a happy ending.If it is not happy,it means that it is not the final result.——上天只会安排的快乐的结局。如果不快乐,说明还不是最后结局 13.The greatest mistake you can make in life is to be continually fearing you will make a mistake.——人生中最大的错误是不断纠结于自己会不会犯错 14.There’s nothing more beautiful than a smile that struggles through tears. ? 世上最美的,莫过于从泪水中挣脱出来的那个微笑。(? 15.Nobody can go back and start a new beginning, but anyone can start now and make a new ending. ?没人能让时光倒流,然后重新再出发,但所有人都可以在今天启程, 去创造一个全新的结局。(----? 16.Love is that condition in which the happiness of another person in essential to your own. ?如果另外一个人的幸福是你幸福的根本所在,这就是爱 17.Being strong doesn't mean having a stony heart,but having a smile through the tears.坚强不是心变硬,是泪在打转还能笑
一、选择题 1.(2016●苏州市)If the customer rings up for me again, please the call to the sales department . A.run through B.look through C.go through D.put through 2.People often make a wish before candles when they celebrate birthday. A.bringing out B.laying out C.finding out D.blowing out 3.—The fire was finally____ in Jilin on June 3. Unfortunately, 119 people lost their lives. —I hope the accident like this won’t happen again. A.put down B.put away C.put out D.put up 4.David promised that he would co me to the party, but he didn’t ________. A.stay up B.grow up C.wake up D.show up 5.As the road to the airport is under repair, we will have to _______ early to get there in time. A.turn off B.take off C.put off D.set off 6.George couldn’t wait to _________ his new car. A.put off B.set off C.take off D.show off 7.________, the Internet was only used by the government. But now it’s widely used in every field. A.As usual B.At first C.After all D.So far 8.—Have you heard that there’s a big fire near y our home last night? — Sure. Luckily, the firemen came quickly and ______ the fire. A.came out B.broke out C.put out D.cut out 9.—Who is your favorite singer, Mike? —TF Boys. They are very ____ boys and girls. A.proud of B.popular with C.strict with D.worried about 10.Millie Beijing now. A.don't live in B.doesn't lives in C.don't lives in D.doesn't live in 11.--- Alice’s room is tidy, isn't it? ---Yes. She always _____ her toys after playing with them. A.looks for B.puts away C.sweeps away D.pays for 12.—What do you think of your English teacher? —She is a good and caring one. Though her teaching style that of most other teachers, she always has more creative teaching methods than others do. A.is similar to B.is similar as C.the same as
---------------本文为精心收集的范文、公文、模板、和其他精品文档,如需本文,请下载-------------- 英文经典句子200句 本文从网络收集而来,上传到平台为了帮到更多的人,如果对您有帮助,请点击下载按钮下载本文档本地收藏,另外祝您生活愉快,工作顺利,幸福安康! 英文经典句子(一): 1、God helps those who help themselves。 ;;;; 天助自助者! 2、A genius is the person who repeats the most times! ;;;; 天才就是重复次数最多的人! 3、It is impossible to defeat a person who never gives up。
;;;; 要打败一个永不放下的人是不可能的! 4、If you don;t try,you will never succeed。 如果你不尝试,你就永远不会成功。 5、What you do today is what matters most。 ;;;; 今日所做的事情是最重要的事情。 6、It is a great honor for me to be here,and to have this opportunity to speak with all of you。
;;;; 十分荣幸来到这儿,并且有这个机会和你们说话。 7、I will greet this day with love in my heart。 ;;;; 我要用全身心的爱来迎接今日。 8、The more failures,the more chances for success。Success is usually the last-minute visitor。 ;;;;; 失败的次数越多,成功的机会越近。成功往往是最终一分钟来的客人。 9、The way to have a better tomorrow is to start working on it today。
英语读书名言名句大全 【篇一:英语读书名言名句大全】 都德:书籍是最好的朋友。在生活中遇到任何困难,都可以向它求助,它们永远不会弃你而去。books are the best friends.no matter what difficulties you meet with in life,you can turn to them for help and they will never discard you. 利希藤贝格:书是一面镜子,如果一只驴子向里面窥视,你不可能 指望正往外看的是圣徒。a book is a mirror ,if an ass peers into it,you can t expect an apostle to look out. 多蒂:你从父母那里学会爱,学会笑,学会走路,可是打开一本书,你会发现你有了翅膀。from your parents you lean love and laughter and how to put one foot before the other.but when books are opened you discover that you have wings. 哈曼:一幢没有书的房子,犹如一个没有窗户的房间。a house without books is like a room without windows. 伯克:阅读不思考犹如吃饭不消化。 reading without reflecting is like eating without digesting. 爱默生:不必告诉我你曾经读过什么书,我可以从你的言谈中察知。不必告诉我你同什么人交往,我可以从你的举止中看出。do not tell me the books you have read,let me glean it from your conversation .do not tell me of the people you associate with,let me observe it by your manners. all books are p> books are the food for the hungry of great mind.书籍是伟大的饥饿的粮食。 books are to mankind what memory is to the inp> books are treasure banks storing wisdom passed down from generation to generation.书籍是贮存人类代代相传的智慧的宝库。 classic a book which people praise and don t read. 经典之作是 人人皆称赞却不愿去读的书。 coping with problems in our real life is the end, and reading is only one of the means to reach the end.处理现实生活是目的,读 书只是达到这个目的手段之一。 高尔基:读书越多,精神就越健壮勇敢。the more you read,the more healthy and brave your spirit will be.
大学英语常用短语常用作文词汇等 一 开头万能公式 1.开头万能公式一:名人名言 有人问了,“我没有记住名言,怎么办?尤其是英语名言?”,很好办:编! 原理:我们看到的东西很多都是创造出来的,包括我们欣赏的文章也是,所以尽管编,但是一定要听起来很有道理呦!而且没准将来我们就是名人呢!对吧?经典句型: A proberb says, “ You are only young once.” (适用于已记住的名言) It goes without saying that we cannot be young forever. (适用于自编名言) 更多经典句型: As everyone knows, No one can deny that… 2.开头万能公式二:数字统计 原理:要想更有说服力,就应该用实际的数字来说明。 原则上在议论文当中十不应该出现虚假数字的,可是在考试的时候哪管那三七二十一,但编无妨,只要我有东西写就万事大吉了。所以不妨试用下面的句型:According to a recent survey, about 78.9% of the college students wanted to further their study after their graduation. 看起来这个数字文邹邹的,其实都是编造出来的,下面随便几个题目我们都可以这样编造: Honesty:根据最近的一项统计调查显示,大学生向老师请假的理由当中78%都是假的。 Travel by Bike:根据最近的一项统计调查显示,85%的人在近距离旅行的时候首选的交通工具是自行车。 Youth:根据最近的一项统计调查显示,在某个大学,学生的课余时间的70%都是在休闲娱乐。 Five-day Work Week Better than Six-day Work?:根据最近的一项统计调查显示,98%的人同意每周五天工作日。 更多句型: A recent statistics shows that … 结尾万能公式 1.结尾万能公式一:如此结论 说完了,毕竟要归纳一番,相信各位都有这样的经历,领导长篇大论,到最后终于冒出个“总而言之”之类的话,我们马上停止开小差,等待领导说结束语。也就是说,开头很好,也必然要有一个精彩的结尾,让读者眼前一亮,这样,你就可以拿高分了!比如下面的例子: Obviously(此为过渡短语), we can draw the conclusion that good manners arise from politeness and respect for others. 如果读者很难“显而见之”,但说无妨,就当读者的眼光太浅罢了! 更多过渡短语:
经典英语励志短语句子 1、trynottobecomeamanofsuccessbutrathertrytobecomeamanofvalue.(a.eins tein)不要为成功而努力,要为作一个有价值的人而努力。 (爱因斯坦)2、thereasonablemanadaptshimselftotheworld;theunreasonableonepersistsin tryingtoadapttheworldtohimself.(bernardshaw)明白事理的人使自己适应世界;不明事理的人想使世界适应自己。 (萧伯钠)3、neverunderestimateyourpowertochangeyourself!永远不要低估你改变自我的能力!4、nothingisimpossible!没有什么不可能!5、nothingfornothing.不费力气,一无所得。 6、themanwhohasmadeuphismindtowinwillneversay"impossible".(bonaparte napoleon,frenchemperor)凡是决心取得胜利的人是从来不说不可能的”。 (法国皇帝拿破仑.b.)7、iwillgreetthisdaywithloveinmyheart.我要用全身心的爱来迎接今天8、dowhatyousay,saywhatyoudo做你说过的,说你能做的9、 icanmakeitthroughtherain.icanstanduponceagainonmyown.我可以穿越云雨,也可以东山再起10、allthingscometothosewhowait.苍天不负有心人11、athousand-lijourneyisstartedbytakingthefirststep.千里之行,始于
100句经典英语句子 导读:本文是关于100句经典英语句子的文章,如果觉得很不错,欢迎点评和分享! 1、别把最爱你的女孩弄丢了,也别等浪够了才知道家没了。 Don't lose the girl who loves you most, and don't wait for enough waves to know that home is gone. 2、你的梦想也许遥不可及,只有坚持,它总有一天可以实现。 Your dream may be out of reach. Only by persevering, it will come true one day. 3、爱要趁早,当时间渐渐擦去心间的触动,一切早已无法弥补。 Love should be early, when time gradually erases the touch between the hearts, everything has long been irreparable. 4、那往昔已如隔夜的梦,散落在这飘渺的夜空,寂静安然。 The past has been like a dream overnight, scattered in the ethereal night sky, quiet and peaceful. 5、爱一个人你会感受到一些难以描绘的情感,也许这就叫幸福吧! If you love someone, you will feel some emotions that are difficult to describe. Maybe this is called happiness. 6、妙笔难书一纸愁肠,苍白的誓言,终究抵不过岁月的遗忘。
经典英语句子大全 A friend is a second self.朋友是另一个我。 · A friend in need is a friend indeed.患难朋友才是真朋友。 · A friend in court is better than a penny in purse.曩中有钱,不如朝中有友。 · A friend exaggerates a man′s virtue, an enemy his crimes.朋友宣扬人的美德,敌人夸大人的罪过。 · A fox may grow grey, but never good.狐狸会变,但本性难移。 · A fool′s heart dances on his lips.愚人心坦荡,挂在嘴唇上。 · A fool′s bolt may sometimes hit the mark.愚者千虑,必有一得。 ·A fool may throw a stone into a well which a hundred wise men cannot pull out.一愚所失,百智难回。 · A fool may give a wise man counsel.愚者千虑,必有一得。 ·A fool may ask more questions in an hour than a wise man can answer in seven years.愚者所问,智者难答。 · A fool can ask more questions than seven wise men can
answer.一愚发问,七智结舌。 · A fool attempting to be witty is an object of profoundest pity.蠢人装聪明,实在最可怜。 · A fool and his money are soon parted.笨蛋难聚财。 · A fool always rushes to the fore.傻瓜总爱强出头。 · A fool always comes short of his reckoning.愚人常缺算计。 · A flow of words is no proof of wisdom.口若悬河不能作为才智的证明。 · Affairs that are done by due degrees are soon ended.事情要安步就班地做,就会很快地做完。 · A fault confessed is half redressed.承认错误,等於改正一半。 · A father is a treasure, a brother is a comfort, but a friend is both.父亲是财富,兄弟是安慰,朋友兼而有之。 · A fall into the pit, a gain in your wit.吃一堑,长一智。 · A faithful friend is hard to find.益友难得。 · A fair face may hide a foul heart.人不可貌相。 · A fair death honours the whole life.死得光明,终身荣耀。 · Adversity successfully overcome is the highest glory.成功地克服困难是最大的光荣。 · Adversity makes strange bedfellows.身处逆境不择友。