https://www.doczj.com/doc/3c8481522.html,
611. 中国热带农业科学院热带作物品种资源研究所/农业部华南作
物基因资源与种质创制重点开放实验室，海南儋州 571737；
2. 海南省艾纳香工程研究中心，海南儋州 571737；
3. 中国中医科学院博士后科研流动站/中药资源中心，北京
100700
…………………胡 璇1,2 王 凯1,2 谢小丽1,2 庞玉新1,2,3#作者简介
胡璇(1986—)，女，硕士，助理研究员，研究方向：南药资源利用研究与开发。#通信作者:庞玉新(1975—)，男，博士，研究员，研究方向：南药资源利用研究与开发。
联系电话：0898 - 23301253
E - mail: mchuxuan@https://www.doczj.com/doc/3c8481522.html,
星点设计 - 效应面法优化艾纳香舒缓修护面膜配方
*采用星点设计 - 效应面法优化艾纳香舒缓修护面膜配方。以甘油、卡波姆、1,3 - 丁二醇质量分数为主要影响因素，以外观评价和高湿低湿不同条件下的保湿性为评价指标，经归一处理后的总评OD 值作为最终效应值，运用多元线性回归及二项式拟合建立指标与因素之间的数学模型，绘制等高线图和效应面图，经效应面法预测最佳配方参数并进行验证。优化后的最佳配方为添加质量分数5.2%的甘油、0.76%的卡波姆、3%的1,3 - 丁二醇，OD 预测值和测定值平均偏差率为4.81%，小于5%。星点设计 - 效应面法优化使用方便，预测性良好，可用于优选艾纳香舒缓修护面
膜的配方。
艾纳香 星点设计 - 效应面法 配方 制备
Optimization of the Formula of Smoothing Repair Mask with Blumea Balsamifera (L.) DC. by Central Composite Design - Response Surface Methodology *
HU Xuan 1,2 WANG Kai 1,2 XIE Xiao - li 1,2 P ANG Yu - xin 1,2,3#
(1. Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences/Key Laboratory of Crop Gene Resources and Germplasm Enhancement in Southern China, Danzhou 571737, Hainan, China; 2. Hainan Provincial Engineering Research Center for Blumea Balsamifera , Danzhou 571737, Hainan, China; 3. Center for Post - Doctoral Research /National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China)
Abstract ： To optimize the formula of smoothing repair mask with Blumea Balsamifera (L.) DC, the mass fraction of glycerinum, carbomer and 1,3 - butanediol were used as the major in ?uence factors. The appearance evaluation and moisture retention under high humidity and low wet conditions were used as evaluation indices. And the overall desirability with normalized process was determined as the ?nal effect value. The mathematical model about index and factors was established by multiple linear regression and binomial fitting. Then overlay contour plots and response surface were delineated. The optimal formulation parameters were predicted by response surface methodology and veri ?ed. The optimal conditions were *基金项目:中国热带农业科学院基本科研业务费专项资金（编号
1630032017071）；非营利性科研机构改革专项启动费项目（编号
pzsfyl201715）
收稿日期： 2017 - 07 - 07；修回日期：2017 - 08 - 14
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