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所致疾病 占人类链球菌感染的90%。传播 方式:飞沫、皮肤伤口、污染食物。 1. 化脓性感染:皮肤和皮下组织感染、其他系 统感染。 2. 中毒性疾病:猩红热、链球菌毒素休克综合 症。 3. 超敏反应性疾病:风湿热、急性肾小球肾炎。
Some of the more prominent diseases associated with group A streptococcal infections, and the body sites affected.
β溶血
α溶血
蛋白质抗原主要为葡萄球菌A蛋白 (staphylococcal protein A,SPA),是细胞壁的 一种表面蛋白,SPA可同哺乳动物IgG分子的Fc段 发生非特异性接合,封闭吞噬细胞与抗体(IgG)包 被的细菌的接合,从而抑制抗体介导的调理吞噬 作用,助长本菌的致病作用。SPA还有促细胞分裂、 引起变态反应、损伤血小板等多种生物活性。
猩红热(Scarlet fever) (scarlatina)
Scarlet fever is a communicable disease spread by inhalation of infective respiratory droplets. After a 2day incubation period, a scarlatinal rash appears on the upper chest and then spreads to the remainder of the body. Along with the rash, the infected individual experiences a sore throat, chills, fever, headache, and a strawberrycolored tongue