★ST段不抬高的急性冠状动脉综合征 ◆非Q波心肌梗死NSTEMI(CK-MB大于正常上限的2倍) ◆不稳定性心绞痛UAP(CK-MB小于正常上限的2倍) ★ST段抬高的急性冠状动脉综合征——
急性Q波心肌梗死STEMI
5/98
急性冠脉综合征(ACS)及其治疗进展
2
国际现状
每年: • > 4 million patients are admitted with
– history / physical exam – electrocardiogram
• Patients are categorized into 3 groups
– non-cardiac chest pain – unstable angina – myocardial infarction
• recent (< 2 months) acceleration of angina (increase in severity of at least one CCSC class to at least CCSC class III)
Canadian Cardiovascular Society Classification
Anti-platelet Therapy
• Clopidogrel氯比格雷
– CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischemic Events)
– nitrates, beta blockers, calcium antagonists
• 抗血栓 therapy
– 抗血小板 therapy • aspirin, ticlopidine, clopidogrel, GP IIb/IIIa inhibitors