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骨纤维异常增殖症
(Fibrous Dysplasia)
• 为原始间叶组织发育异常。FD is a developmental
anomaly of bone forming mesenchyme.
• 多数病例发生于2-30岁。Mostly be seen between
the ages of 2 and 30.
with a limp, pain, fracture, or deformity.Cafe´-au-lait spots
are seen in over 50% of patients. There is a propensity to
involve one side of the body more extensively.
• 中央性骨透亮区,伴骨皮质变薄和中度骨 膨胀改变。Centrally located radiolucent lesion
with cortical thinning and mild osseous expansion
• 20%出现“骨片陷落征”。 “Fallen fragment”
sign may be seen in 20% of cases
• 70-80%为单发,无临床症状.70-80% of cases are
monostotic and asymptomatic.
• 20-30%为多发型,多见于10岁前,常发生跛行、
疼痛、骨折或畸形,50%以上可见皮肤牛奶咖
啡斑,且有一侧身体受累更广泛的倾向。20-30%
are polyostotic, and present before the age of 10, often
骨骼肌肉系统疾病--液 液平面征