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小分子RNA测序分析

small RNA

5

1.

small RNA

2.

small RNA

small RNA

small RNA

53

35

5

3

small RNA

1. RNA small

small RNA

2. microRNA

microRNA

3. small RNA

microRNA

RNA

4. small

RNA

5-5 small RNA

eat

Total reads annotation

exon_antisense exon_sense intron_antisense intron_sense miRNA rRNAetc rep eat snRNA snoRNA tRNA unann

Unique reads annotation

small RNA

5. microRNA

microRNA

6. MicroRNA

microRNA

small RNA

microRNA

2244

Log2(Treatment/control):

-4 0 4

Gray indicates missing data:

microRNA

microRNA

small RNA

1. Chen X, Li QB, Wang J, et al. Identification and characterization of novel amphioxus microRNAs by Solexa sequencing. Genome Biology. 2009. 10(7): R78 (1-13).

2. Chen X, Ba Y , Ma LJ, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Research. 2008. 18: 997-1006.

3. Mi S, Cai T , Hu Y , Chen Y , et al. Sorting of Small RNAs into Arabidopsis Argonaute Complexes Is Directed by the 5' T erminal Nucleotide. Cell. 2008. 133(1): 116-127.

4. Montgomery TA, Howell MD, et al. Specificity of ARGONAUTE7-miR390 Interaction and Dual Functionality in TAS3 Trans-Acting siRNA Formation. Cell. 2008. 133(1): 128-141.

5. Morin RD, O'Connor MD, et al. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res. 2008. 18: 610-621.

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